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The Journal of Physiology, EarlyView.Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker +2 more
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The Journal of Physiology, EarlyView.Abstract figure legend Illustration of cellular and molecular cross‐talk in atrial fibrillation. Left: a schematic of cardiac tissue showing cardiomyocytes, fibroblasts, adipocytes, inflammatory cells and the coagulation system. Right: direct and indirect cross‐talk between different cell types, with the impact of direct cross‐talk on action potential (
Zhenyu Dong +2 more
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The Journal of Physiology, EarlyView.Abstract figure legend In silico trials were conducted in 654 virtual patients with atrial fibrillation (AF) to assess the cardioversion efficacy of three pharmacological treatments: single SK and K2P channel block and combined SK+K2P channel inhibition. Left: representative virtual AF patient with the atria inside the torso.
Albert Dasí +4 more
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Advances in cardiac devices and bioelectronics augmented with artificial intelligence
The Journal of Physiology, EarlyView.Abstract figure legend Interfaces between the human heart, diagnostic bioelectronics, artificial intelligence, and clinical care. From left to right: Human heart and biosensor interface; representative waveforms of common diagnostic bioelectronic sensing modalities.
Charles Stark +3 more
wiley +1 more source
The cardiac pacemakers: A paradigm of robustness in evolutionary biology
The Journal of Physiology, EarlyView.Abstract figure legend Functional networks in living systems are formed by many thousands of gene products. In association with those networks, several genes (four in this diagram) may be sufficient, each on its own, to ensure that the function occurs. Any one of these may be removed or blocked while leaving the others to continue functioning.
Denis Noble
wiley +1 more source
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Computer Methods in Biomechanics and Biomedical Engineering, 2020
Effective monitoring of heart patients according to heart signals can save a huge amount of life. In the last decade, the classification and prediction of heart diseases according to ECG signals has gained great importance for patients and doctors.
A. Cinar, S. Tuncer
semanticscholar +1 more source
Effective monitoring of heart patients according to heart signals can save a huge amount of life. In the last decade, the classification and prediction of heart diseases according to ECG signals has gained great importance for patients and doctors.
A. Cinar, S. Tuncer
semanticscholar +1 more source
Science Translational Medicine, 2019
An implanted light source coupled with local gene therapy generates an automated shock-free system to treat atrial fibrillation in rats. Atrial fibrillation treatment lightens up Atrial fibrillation is an irregular, rapid heartbeat that interrupts normal
E. Nyns +11 more
semanticscholar +1 more source
An implanted light source coupled with local gene therapy generates an automated shock-free system to treat atrial fibrillation in rats. Atrial fibrillation treatment lightens up Atrial fibrillation is an irregular, rapid heartbeat that interrupts normal
E. Nyns +11 more
semanticscholar +1 more source