Results 191 to 200 of about 111,116 (318)

Long‐Term Safety and Efficacy of Mepolizumab in Eosinophilic Granulomatosis With Polyangiitis

open access: yesArthritis &Rheumatology, Volume 77, Issue 8, Page 1052-1062, August 2025.
Objective Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare, relapsing, inflammatory disease. Management of EGPA predominantly relies on oral corticosteroids (OCS), which are associated with many adverse effects. The phase 3 MIRRA trial demonstrated efficacy and safety of mepolizumab, anti‐interleukin‐5 biologic, for EGPA.
Michael E. Wechsler   +34 more
wiley   +1 more source

Ofatumumab for the Treatment of Anti‐Neurofascin 155 Autoimmune Nodopathy: A Case Series

open access: yesBrain and Behavior, Volume 15, Issue 8, August 2025.
Summarize the key messages of this paper Ofatumumab treatment led to significant clinical, imaging, and electrophysiological improvements in four patients with anti‐NF155 AN.1. No adverse reactions to ofatumumab were observed in any of the patients. Ofatumumab has great potential for treating anti‐NF155 AN.3. ABSTRACT Introduction Autoimmune nodopathy (
Kalam Choi   +3 more
wiley   +1 more source

Benralizumab Depletes IL‐5Rα‐Bearing Cells in Skin Lesions of Patients With Atopic Dermatitis

open access: yesClinical and Translational Allergy, Volume 15, Issue 8, August 2025.
ABSTRACT Background Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by tissue eosinophilia and itch. We evaluated the effect of eosinophil depletion with benralizumab on markers of inflammation in the skin of patients with AD. Methods After a 4‐week washout from oral anti‐inflammatory medications 20 patients with moderate to
Christiane E. Whetstone   +15 more
wiley   +1 more source

Validation of existing clinical prediction rules and factors predicting radiological traumatic brain injury among pediatric patients presenting with head injury to emergency department

open access: yesHong Kong Journal of Emergency Medicine, Volume 32, Issue 4, August 2025.
Abstract Introduction Existing clinical prediction rules (CPRs) for pediatric head injury such as PECARN, CATCH, and CHALICE primarily focus on clinically important TBIs, neglecting milder forms of brain injuries with prognostic significance. We aimed to bridge this gap by evaluating also patients with milder brain injuries.
Ho Han Mak   +3 more
wiley   +1 more source

<i>Capnocytophaga sputigena</i> Causing Complicated Sinusitis With Intracranial Involvement in a Pediatric Patient. [PDF]

open access: yesCase Rep Otolaryngol
Gandhi K   +6 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy