Long‐Term Safety and Efficacy of Mepolizumab in Eosinophilic Granulomatosis With Polyangiitis
Objective Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare, relapsing, inflammatory disease. Management of EGPA predominantly relies on oral corticosteroids (OCS), which are associated with many adverse effects. The phase 3 MIRRA trial demonstrated efficacy and safety of mepolizumab, anti‐interleukin‐5 biologic, for EGPA.
Michael E. Wechsler+34 more
wiley +1 more source
Outpatient antibiotic stewardship during the COVID-19 era: analysis of prescribing trends and guideline compliance. [PDF]
Sohn M+3 more
europepmc +1 more source
Ofatumumab for the Treatment of Anti‐Neurofascin 155 Autoimmune Nodopathy: A Case Series
Summarize the key messages of this paper Ofatumumab treatment led to significant clinical, imaging, and electrophysiological improvements in four patients with anti‐NF155 AN.1. No adverse reactions to ofatumumab were observed in any of the patients. Ofatumumab has great potential for treating anti‐NF155 AN.3. ABSTRACT Introduction Autoimmune nodopathy (
Kalam Choi+3 more
wiley +1 more source
Microbiological Comparison of Maxillary Sinus Rinses in Non-Odontogenic and Odontogenic Sinusitis of Primarily Endodontic Origin. [PDF]
Kwiatkowska MA+5 more
europepmc +1 more source
A Case of Granulomatosis With Polyangiitis Mimicking Chronic Sinusitis With Polyp. [PDF]
Oh M, Heo SJ.
europepmc +1 more source
Benralizumab Depletes IL‐5Rα‐Bearing Cells in Skin Lesions of Patients With Atopic Dermatitis
ABSTRACT Background Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by tissue eosinophilia and itch. We evaluated the effect of eosinophil depletion with benralizumab on markers of inflammation in the skin of patients with AD. Methods After a 4‐week washout from oral anti‐inflammatory medications 20 patients with moderate to
Christiane E. Whetstone+15 more
wiley +1 more source
Treatment of non-chronic odontogenic sinusitis: maxillary sinus lavage via extraction socket after tooth or implant removal. [PDF]
Kim JY, Yun PY, Ku JK.
europepmc +1 more source
Abstract Introduction Existing clinical prediction rules (CPRs) for pediatric head injury such as PECARN, CATCH, and CHALICE primarily focus on clinically important TBIs, neglecting milder forms of brain injuries with prognostic significance. We aimed to bridge this gap by evaluating also patients with milder brain injuries.
Ho Han Mak+3 more
wiley +1 more source
<i>Capnocytophaga sputigena</i> Causing Complicated Sinusitis With Intracranial Involvement in a Pediatric Patient. [PDF]
Gandhi K+6 more
europepmc +1 more source