Results 231 to 240 of about 116,720 (351)

Science and sinuses [PDF]

open access: yesThe Journal of Bone and Joint Surgery. British volume, 1997
openaire   +2 more sources

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1405-1421, December 2025.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami   +2 more
wiley   +1 more source

Rehabilitation of the Atrophic Edentulous Maxilla: A Retrospective Cohort Study Comparing Survival of Delayed‐Loaded Implants in Grafted Bone Versus Immediately Loaded Implants in Native Bone

open access: yesClinical and Experimental Dental Research, Volume 11, Issue 6, December 2025.
ABSTRACT Objectives This retrospective cohort study aimed to assess the survival rate of implants placed in grafted edentulous maxillary arches following a delayed loading protocol versus a graftless approach with an immediate loading protocol. Materials and Methods Eighty seven patients with atrophic edentulous maxillae were included in two groups ...
Evelina Haroyan‐Darbinyan   +6 more
wiley   +1 more source

Australian Real‐World Effectiveness and Safety of Ustekinumab for the Treatment of Crohn's Disease: Results of the AURORA Study, Including the ANZIBD Consortium

open access: yesJGH Open, Volume 9, Issue 12, December 2025.
ABSTRACT Background Ustekinumab is an effective therapy for the management of Crohn's disease. Australia is unique, as ustekinumab can be prescribed as first‐line biologic therapy, and there is high concomitant immunomodulator use. Aim To evaluate the real‐world efficacy and safety of ustekinumab in moderate to severe Crohn's disease.
Yoon‐Kyo An   +29 more
wiley   +1 more source

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