Results 131 to 140 of about 570,641 (287)

Population pharmacokinetics of TBAJ‐587 and its main metabolites—Evaluation of different loading dose strategies and early dose selection

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background and Aim The rise of drug‐resistant tuberculosis (TB) poses a need for new drugs and combinations. TBAJ‐587, a new diarylquinoline (DARQ), has shown promising efficacy in preclinical studies. This work aimed to describe the pharmacokinetics (PK) of TBAJ‐587 and its metabolites M2 and M3 after single ascending dosing in healthy volunteers and ...
Albin A. M. Leding   +6 more
wiley   +1 more source

The SIR Model Family

open access: yes, 2017
An introduction to the susceptible-infected-recovered compartmental model of infectious disease transmission.
openaire   +1 more source

Mathematical modeling of the spread of the coronavirus under strict social restrictions

open access: yesMathematical Methods in the Applied Sciences, EarlyView., 2021
We formulate a simple susceptible‐infectious‐recovery (SIR) model to describe the spread of the coronavirus under strict social restrictions. The transmission rate in this model is exponentially decreasing with time. We find a formula for basic reproduction function and estimate the maximum number of daily infected individuals.
Mo'tassem Al‐arydah   +3 more
wiley   +1 more source

An epidemiological model of SIR in a nanotechnological innovation environment

open access: yesHeliyon
Today, when nanotechnological innovation, in particular, faces stringent regulations, the question arises concerning a tool that can quantify individual interventions and thus complement current knowledge in the diffusion theory of innovation. This paper
David Svoboda   +3 more
doaj   +1 more source

‘Let's talk about the weather’: The activist curriculum and global climate change education

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Activist movements have garnered significant global attention on a range of sustainability issues, often involving collectives of citizens coming together. Invoked is the idea of citizens informed to act, emerging not from a common‐sense understanding of everyday life, but rather from a deep political understanding of the world—one that is ...
Richard Pountney
wiley   +1 more source

An SIR model with viral load-dependent transmission. [PDF]

open access: yesJ Math Biol, 2023
Della Marca R, Loy N, Tosin A.
europepmc   +1 more source

International student agency in academic self‐formation: Mobility as agency situated within knowledge structures

open access: yesBritish Educational Research Journal, EarlyView.
Abstract With growing attention to student agency in academic and policy discourse, international education has become a prominent context for examining how students navigate new cultural, academic, linguistic and social environments. However, much of this discussion attributes student agency to the ‘international’ aspect, while overlooking the ...
Soyoung Lee
wiley   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

open access: yesBMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen   +7 more
wiley   +1 more source

Delay infectivity and delay recovery SIR model

open access: yesPhysica A: Statistical Mechanics and its Applications
We have derived the governing equations for an SIR model with delay terms in both the infectivity and recovery of the disease. The equations are derived by modelling the dynamics as a continuous time random walk, where individuals move between the classic SIR compartments.
C.N. Angstmann   +3 more
openaire   +3 more sources

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