Results 131 to 140 of about 39,047,150 (349)

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

Advanced Science, EarlyView.
Chronic stress reshapes the gut microbiota and enriches Lactobacillus reuteri, promoting microbiota‐associated kynurenine accumulation through altered tryptophan metabolism. Kynurenine drives immunosuppressive remodeling of tumor‐associated macrophages through TNFR2–C/EBPβ signaling, thereby enhancing gastric cancer dissemination.
Sicheng Zhao, Zhiyuan Song, Jingcheng Zhang, Jiaheng Lou, Shuo Zhang, Boqiang Liu, Yunhai Wei, Fengmei Qiu, Tao Jiang, Guangji Zhang   +9 more
wiley   +1 more source

[Penguins coming up the beach, Australasian Antarctic Expedition, 1911-1914] [picture]

, 1911
Inscription: "C.135 (Mawson 3)"--In pencil on verso.; Part of collection: Sir Douglas Mawson collection of Antarctic photographs.; Condition: Good.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic ...
Mawson, Douglas, Sir, 1882-1958.
core  

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

Advanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang, Jian‐Tong Shen, Hua‐Hua Zhang, Si‐Qi Gao, Ji‐Ao Wang, Yue‐Ling Wang, Mei‐Ling Li, Zi‐Meng Liu, Yi‐Nan Zhang, Yan Li, Xu‐Yu Zhang   +10 more
wiley   +1 more source

Melbourne Harbour Trust. Drawing no. 5, Longitudinal and cross sections of works : recommended by Sir John Coode in his report of 17th Feby. 1879 [cartographic material].

, 1879
Map of harbour works to be undertaken by Melbourne Harbour Trust as attached to Sir John Coode's report. Relief shown by bathymetric soundings. Fig. no. 1 Longitudinal section of the proposed channel between Melbourne and Hobson's Bay -- Fig. no. 2 Cross
Coode, John, Sir.
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RBM25 Drives Hepatocellular Carcinoma Progression by Stabilizing YAP Through Regulating Oncogenic Splicing‐switch of MYPT1

Advanced Science, EarlyView.
This study establishes that the RBM25‐PRPF40A interaction modulates MYPT1 splicing, promoting the production of the oncogenic long isoform. This isoform stabilizes YAP by suppressing its phosphorylation and subsequent proteasomal degradation, ultimately accelerating tumor growth.
Wenjing Zhang, Lili Zhi, Tian Huang, Lingya Feng, Chaoqun Chen, Huanhuan Wei, Xiaolong Liu, Lei Chen, Jinrui Zhang, Ge Zhang, Baofeng Zhao, Rong Liu, Dan Chen, Yangfan Qi, Yang Wang   +14 more
wiley   +1 more source

Ross & D'Urville, pupps [i.e. pups] at the Cape Denison Station, [Australasian Antarctic Expedition, 1911-1914] [picture] /

, 1911
Inscription: "C. 97 (Mawson 119)"--In pencil on verso.; Part of collection: Sir Douglas Mawson collection of Antarctic photographs.; Condition: Good.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic ...
Mawson, Douglas, Sir, 1882-1958.
core  

Guidelines for High‐Throughput Screening for Natural Products With Anti‐Aging Activity Based on Drosophila Intestinal Homeostasis

AgriFood: Journal of Agricultural Products for Food, EarlyView.
ABSTRACT Aging represents a critical risk factor for chronic diseases, driving an urgent demand for interventions promoting healthy longevity. This study establishes standardized guidelines for high‐throughput screening (HTS) of anti‐aging natural products using Drosophila melanogaster, leveraging its intestinal homeostasis as a biomarker.
Xiao Sheng, Lei Zhang
wiley   +1 more source

Lettre de sir James Kempt à sir J.C. Sherbrooke sur les services rendus par H. W. Ryland pendant les administrations de lord Dorchester et de sir James Craig

4 pages, copie manuscriteLettre de sir James Kempt à sir J.C. Sherbrooke sur: les services rendus par [H. W.] Ryland pendant les administrations de lord Dorchester et de sir James Craig; les avantages que Sherbrooke pourrait donner aux fils de Ryland; le
Kempt, James, sir;
core   +1 more source

A Floquet-Style Stability Analysis of the Disease-Free State in a Seasonal Hantavirus Model

Mathematics
In this study, we developed an SIR-like mathematical model of disease transmission dynamics. Hantavirus is a neglected tropical disease, and this paper presents a mathematical model of hantavirus transmission among rodents and its effect on the number of
Asep K. Supriatna, Dwi Agustian, Maya Rayungsari, Hennie Husniah, Riana N. Pakpahan   +4 more
doaj   +1 more source

[Close up view of a bare hillside, Australasian Antarctic Expedition, 1911-1914] [picture]

, 1911
Inscription: "H.369 (Blake 4 )"--In pencil on verso.; Part of collection: Sir Douglas Mawson collection of Antarctic photographs.; Condition: Good.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic ...
Mawson, Douglas, Sir, 1882-1958.
core