Results 81 to 90 of about 39,047,150 (349)
Frontiers in Applied Mathematics and Statistics, 2021 The COVID-19 pandemic has had worldwide devastating effects on human lives, highlighting the need for tools to predict its development. The dynamics of such public-health threats can often be efficiently analyzed through simple models that help to make ...
P.L. de Andres +2 more
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
medRxiv, 2020 Mathematical modeling is a process aimed at finding a mathematical description of a system and translating it into a relational expression. When a system is continuously changing over time (e.g., infectious diseases)differential equations, which may ...
Hyeontae Jo +3 more
semanticscholar +1 more source
Model-based SIR for dimension reduction [PDF]
Computational Statistics & Data Analysis, 2011 A new dimension reduction method based on Gaussian finite mixtures is proposed as an extension to sliced inverse regression (SIR). The model-based SIR (MSIR) approach allows the main limitation of SIR to be overcome, i.e., failure in the presence of regression symmetric relationships, without the need to impose further assumptions.
openaire +5 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Stochastic Modeling of a Measles Outbreak in Brazil
Trends in Computational and Applied Mathematics, 2023 Development of mathematical models and its numerical implementations are essential tools in epidemiological modeling. Susceptible-Infected-Recovered (SIR) compartmental model, proposed by Kermack and McKendrick, in 1927, is a widely used deterministic ...
M. Lau, Z. G. Arenas
doaj +1 more source
Measuring and Preventing COVID-19 Using the SIR Model and Machine Learning in Smart Health Care
Journal of Healthcare Engineering, 2020 COVID-19 presents an urgent global challenge because of its contagious nature, frequently changing characteristics, and the lack of a vaccine or effective medicines.
S. Alanazi +5 more
semanticscholar +1 more source
Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu +11 more
wiley +1 more source
A death, infection, and recovery (DIR) model to forecast the COVID-19 spread
Computer Methods and Programs in Biomedicine Update, 2022 Background: The SARS-Cov-2 virus (commonly known as COVID-19) has resulted in substantial casualties in many countries. The first case of COVID-19 was reported in China towards the end of 2019.
Fazila Shams +4 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source