Results 111 to 120 of about 82,161 (336)
Antilymphoid antibody preconditioning and tacrolimus monotherapy for pediatric kidney transplantation [PDF]
Objective: Heavy post-transplant immunosuppression may contribute to long-term immunosuppression dependence by subverting tolerogenic mechanisms; thus, we sought to determine if this undesirable consequence could be mitigated by pretransplant lymphoid ...
Abhay N. Vats+52 more
core +1 more source
Abstract Belumosudil is an oral selective rho‐associated coiled‐coil containing protein kinase 2 inhibitor, approved as a treatment for chronic graft‐versus‐host disease. Prior clinical studies demonstrated that coadministration with strong CYP3A4 inducers or proton pump inhibitors requires dose modification of belumosudil.
Olivier Schueller+4 more
wiley +1 more source
Sirolimus Eluting Stents [PDF]
The sirolimus-eluting stent (SES) Cypher was the first commercially available drug-eluting stent. The use of this stent has resulted in significantly lower rates of restenosis and lesion revascularization compared to bare metal stents and balloon angioplasty.
Ehtisham Mahmud, Patrick Hu
openaire +1 more source
A Surgical Perspective on Targeted Therapy of Hepatocellular Carcinoma. [PDF]
Hepatocellular carcinoma (HCC), the second leading cause of cancer deaths worldwide, is difficult to treat and highly lethal. Since HCC is predominantly diagnosed in patients with cirrhosis, treatment planning must consider both the severity of liver ...
Busuttil, Ronald W+2 more
core +2 more sources
Abstract Graft versus host disease (GVHD) is a complication that frequently occurs after haematopoietic stem cell transplantation and concerns many children in paediatric haematology‐oncology and bone marrow transplantation departments. It can affect various organs, with the skin, gastrointestinal tract and liver being the most commonly involved.
Marina Vincent+12 more
wiley +1 more source
Background. We have reported previously the insufficient absolute number or functional defects of regulatory T cells (Tregs) in patients with rheumatoid arthritis (RA), challenging conventional unspecific immunosuppressive therapy.
Hong-Yan Wen+19 more
doaj +1 more source
Abstract Gastrointestinal (GI) bleeding can be a common symptom in the pediatric population. Vascular malformations, which cause symptoms based on their location and effect on surrounding structures, are an uncommon cause of GI bleeding. We present the case of a 6‐year‐old male with a 1‐year history of hematochezia, constipation, and microcytic anemia.
Kathleen Ordas+5 more
wiley +1 more source
Min-Soo Kim1, Jeong-Soo Kim1, Hee Jun Park1, Won Kyung Cho1,3, Kwang-Ho Cha1,3, Sung-Joo Hwang2,31College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea, 2College of Pharmacy, 3Yonsei Institute of Pharmaceutical Sciences, Yonsei ...
Kim MS+5 more
doaj
Macromolecular approaches to prevent thrombosis and intimal hyperplasia following percutaneous coronary intervention. [PDF]
Cardiovascular disease remains one of the largest contributors to death worldwide. Improvements in cardiovascular technology leading to the current generation of drug-eluting stents, bioresorbable stents, and drug-eluting balloons, coupled with advances ...
Panitch, Alyssa, Scott, Rebecca A
core +2 more sources
Elevated tissue transglutaminase immunoglobulin A: Celiac disease or polytypic plasmacytosis?
Abstract We report a case of an adolescent girl post cardiac transplant with hypergammaglobulinemia and presumed celiac disease (CD), who had a persistently elevated anti‐tissue transglutaminase immunoglobulin A despite a gluten free diet. Refractory CD and Crohn's disease were excluded.
Andrew Turunen+4 more
wiley +1 more source