Results 111 to 120 of about 117,912 (291)

Kaposiform hemangioendothelioma: Diagnosis and treatment

Pediatric Investigation, EarlyView.
Vascular endothelial growth factor‐C (VEGF‐C)/vascular endothelial growth factor receptor‐3 (VEGFR‐3) and angiopoietin‐2 (Ang‐2)/tyrosine kinase with immunoglobulin‐like and EGF‐like domain 2 (TIE2) signaling pathways play an important role in lymphangiogenesis.
Yi Tian, Yuanyuan Tian, Li Wei, Zigang Xu, Li Li, Lin Ma   +5 more
wiley   +1 more source

Enhanced bioavailability of sirolimus via preparation of solid dispersion nanoparticles using a supercritical antisolvent process

International Journal of Nanomedicine, 2011
Min-Soo Kim1, Jeong-Soo Kim1, Hee Jun Park1, Won Kyung Cho1,3, Kwang-Ho Cha1,3, Sung-Joo Hwang2,31College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea, 2College of Pharmacy, 3Yonsei Institute of Pharmaceutical Sciences, Yonsei ...
Kim MS, Kim JS, Park HJ, Cho WK, Cha KH, Hwang SJ   +5 more
doaj  

Sirolimus increases tissue factor expression but not activity in cultured human vascular smooth muscle cells

BMC Cardiovascular Disorders, 2005
Background Sirolimus-eluting stents (CYPHER stents) demonstrated remarkable efficacy in reducing restenosis rates in patients with coronary artery disease. There is a concern of sub-acute and late stent thrombosis.
Ming Xiu-Fen, Gajanayake Thusitha, Viswambharan Hema, Zhu Shengsi, Yang Zhihong   +4 more
doaj   +1 more source

Additive value of transarterial embolization to systemic sirolimus treatment in kaposiform hemangioendothelioma

International Journal of Cancer, 2020
Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor in children, which can be accompanied by life‐threatening thrombocytopenia, referred to as Kasabach‐Merritt phenomenon (KMP).
R. Brill, W. Uller, V. Huf, R. Müller-Wille, I. Schmid, A. Pohl, B. Häberle, Sybille Perkowski, K. Funke, A. Till, M. Lauten, J. Neumann, C. Güttel, Esther Heid, Franziska Ziermann, A. Schmid, Dieter Hüsemann, Lutz Meyer, P. Sporns, R. Schinner, V. Schmidt, J. Ricke, J. Rössler, Friedrich G. Kapp, W. Wohlgemuth, M. Wildgruber   +25 more
semanticscholar   +1 more source

Treatment of pediatric epilepsy

Pediatric Investigation, EarlyView.
Anti‐seizure medications are the first‐line treatment for the vast majority of children with epilepsy, with the advantages of non‐invasive wide adaptability. Surgery is the main treatment for drug‐resistant epilepsy and lesion‐related epilepsy, which can cure some cases of epilepsy in children. A ketogenic diet is often an add‐on therapy.
Junxiao Li, Tinghong Liu, Chang Liu, Jie Deng, Shijie Wu, Suhui Kuang, Xiaotong Li, Zhirong Wei, Shuli Liang   +8 more
wiley   +1 more source

Guidance on Noncorticosteroid Systemic Immunomodulatory Therapy in Noninfectious Uveitis : Fundamentals Of Care for UveitiS (FOCUS) Initiative [PDF]

, 2018
Supplemental material available at www.aaojournal.org. Supported by AbbVie, Inc., and the Fundamentals of Care for Uveitis Initiative National Faculty.
Accorinti, Massimo, Acharya, Nisha, Adan, Alfredo, Agrawal, Rupesh, Akkoc, Nurullah, Al Ghamdi, Saed, Al Ghamdi, Turki, Al Saati, Anood, Al-Dhibi, Hassan A., Al-Shamarani, Mohamed, Alsabaani, Nasser, Bachta, Artur, Barisani-Asenbauer, Talin, Beare, Nicholas, Belfort, Rubens, Blanco, Ricardo, Brézin, Antoine P., Carreño, Ester, Chandran, Vinod, Chee, Soon Phaik, Chiquet, Christophe, Chng, Hiok Hee, Cimbalas, Andrius, Cimino, Luca, Cordero-Coma, Miguel, Cristobal, Couto, Cuevas, Miguel, Davis, Janet L., de Boer, Joke, de la Torre, Alejandra, De Schryver, Ilse, Derzko-Dzulynsky, Larissa, Diaz-Valle, David, Dick, Andrew D., Eurico da Fonseca, João, Facsko, Andrea, Figueira, Luis, Fundamentals of Care for Uveitis International Consensus Group, Kuffova, Lucia, Merino, Claudia Eugenia Duran, Murphy, Conor, Nascimento, Heloisa, Porto, Fernanda Belga Ottoni, Ramanan, Athimalaipet V., Rosenbaum, James T., Salah, Sawsen, Salek, Sherveen, Siak, Jay, Sonoda, Koh Hei, Steeples, Laura, Yee, Anita Chan Sook   +50 more
core   +1 more source

Systematic review with meta‐analysis: sirolimus‐ or everolimus‐based immunosuppression following liver transplantation for hepatocellular carcinoma

Alimentary Pharmacology and Therapeutics, 2019
Calcineurin‐inhibitor immunosuppressants (tacrolimus and ciclosporin) have been associated with an exposure‐related increase in tumour recurrence following liver transplantation for hepatocellular carcinoma (HCC).
S. Grigg, G. Sarri, P. Gow, N. Yeomans
semanticscholar   +1 more source

Synergistic antiviral activity against human adenovirus through combination of itraconazole and brincidofovir

British Journal of Pharmacology, EarlyView.
Background and Purpose Human adenovirus (HAdV) causes respiratory or gastrointestinal tract infections depending on the virus subtype. While HAdV infections are generally self‐limiting in immunocompetent people, they can result in significant morbidity and mortality in immunocompromised adults and children.
Mohamed Zamzamy, Sophie Post, Wing Hang Ip, Elin Hahlin, Sebastian Kühn, Andrea Pirosu, Christian Conze, Martin Baumdick, Hamburg Intestinal Study Group, Madeleine J. Bunders, Britta F. Zecher, Angelique Hoelzemer, Stephan Linder, Niklas Arnberg, Thomas Dobner, Marcus Altfeld, Sebastian Schloer   +16 more
wiley   +1 more source

Safety and tolerability of sirolimus treatment in patients with autosomal dominant polycystic kidney disease [PDF]

, 2017
Background. We initiated a randomized controlled clinical trial to assess the effect of sirolimus on disease progression in patients affected by autosomal dominant polycystic kidney disease (ADPKD).
Kistler, Andreas D., Krauer, Fabienne, Pavik, Ivana, Poster, Diane, Raina, Shagun, Regeniter, Axel, Rentsch, Katharina, Senn, Oliver, Serra, Andreas L., Weishaupt, Dominik, Wüthrich, Rudolf P.   +10 more
core  

Randomized Comparison of Everolimus-Eluting and Sirolimus-Eluting Stents in Patients Treated With Percutaneous Coronary Intervention: The Scandinavian Organization for Randomized Trials With Clinical Outcome IV (SORT OUT IV) [PDF]

, 2012
BACKGROUND: Among drug-eluting stents released to date, the sirolimus-eluting stent has demonstrated the least amount of late lumen loss, but its efficacy and safety have not been compared head-to-head with the next-generation everolimus-eluting stent ...
Aarøe, Jens, Boel Villadsen, Anton, Bøtker, Hans Erik, Christiansen, Evald Høj, Hansen, Hans-Henrik Tilsted, Hansen, Henrik Steen, Junker, Anders, Kaltoft, Anne, Kristensen, Steen Dalby, Krusell, Lars Romer, Lassen, Jens Flensted, Madsen, Morten, Maeng, Michael, Nørregaard Hansen, Knud, Okkels Jensen, Lisette, Pedersen, Knud Erik, Ravkilde, Jan, Sanchez, Richardo, Sørensen, Henrik Toft, Thayssen, Per, Thuesen, Leif   +20 more
core   +1 more source