ERSAtool: A User-Friendly R/Shiny Comprehensive Transcriptomic Analysis Interface Suitable for Education. [PDF]
The Educational RNA‐Seq Analysis tool (ERSAtool) provides a comprehensive R/Shiny interface with an intuitive graphical visualization of the entire RNA‐seq analysis pipeline, enabling users to perform complex transcriptomic analyses with less technical expertise.
Taridalu S, Kameshwar AKS, Suzuki M.
europepmc +2 more sources
Preterm Birth Increases Susceptibility to Hyperglycemia-Induced Kidney Injury With Sex-Specific Differences in Structural and Molecular Responses. [PDF]
Preterm mice were delivered at 19 dpc and rendered diabetic with STZ at 6 weeks; kidneys were analysed at 18 weeks. PT‐D females showed increased atubular glomeruli, reduced proximal tubule fraction, higher albuminuria and BUN, and dysregulated fibrotic, vascular, mitochondrial, and Notch pathways.
Dailey RK +13 more
europepmc +2 more sources
Quantitative Systems Toxicology Modeling of Acetaminophen Pharmacokinetics and Hepatic Biomarkers After Overdoses of Extended-Release and Immediate-Release Formulations in Adults With Chronic Alcohol Use or Low Glutathione. [PDF]
ABSTRACT Acetaminophen (APAP), an over‐the‐counter analgesic and antipyretic, can cause hepatotoxicity when ingested in large overdoses. APAP has multiple formulations including immediate‐release (IR) and extended‐release (ER) preparations. A recently published consensus statement on the management of APAP poisoning indicated that management of APAP‐ER
Yang K +8 more
europepmc +2 more sources
Enhanced Laser-Induced Graphene Microfluidic Integrated Sensors (LIGMIS) for On-Site Biomedical and Environmental Monitoring. [PDF]
A laser‐induced graphene microfluidic with integrated sensors (LIGMIS) are demonstrated for practical use in agricultural and biomedical domains. The porous electrodes are modified with silver nanoplatelets and gold microstructured trees for increased electroactive surface area while ion electrodes are modified with solid‐contact membranes for analyte ...
Johnson ZT +12 more
europepmc +2 more sources
Modeling and Simulation of Acetaminophen Pharmacokinetics and Hepatic Biomarkers After Overdoses of Extended-Release and Immediate-Release Formulations in Healthy Adults Using the Quantitative Systems Toxicology Software Platform DILIsym. [PDF]
ABSTRACT Acetaminophen (APAP) has been formulated as immediate‐, modified‐, and extended‐release tablets (APAP‐IR, ‐MR, and ‐ER, respectively). However, there was concern that APAP‐MR previously available in Europe could form a bezoar after a large overdose, leading to delayed absorption and atypical pharmacokinetics (PK) compared to APAP‐IR, and that ...
Beaudoin JJ +9 more
europepmc +2 more sources
Fully integrated digital microfluidics platform for automated immunoassay; a versatile tool for rapid, specific detection of a wide range of pathogens [PDF]
© 2018 Elsevier Ltd. All rights reserved. This manuscript is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence http://creativecommons.org/licenses/by-nc-nd/4.0/.With the tangible threat posed by the ...
Coudron, Loic +6 more
core +2 more sources
Space, Place, Common Wounds and Boundaries: Insider/Outsider Debates in Research with Black Women and Deaf Women [PDF]
The chapter discusses issues of identity in research. It does this by examining the impacts of the identity of the researcher, participants, and the various identity interchanges that take place.
Obasi, Chijioke
core +2 more sources
Att förbereda sig inför den sista resan
This essay is dealing with how to prepare yourself to your own death and the starting point of the discussion is the author´s self-narration. The research perspective is inspired by discursive psychology where no clear distinction is made between ...
Marianne Liliequist
doaj +1 more source
PROFITABILITAS TERHADAP RETURN SAHAM
The development of the capital market is currently followed by the development of the stock market is increasingly in demand by investors as well, seen from data on Indonesia Stock Exchange (IDX) which shows that the stocks included in the sharia has ...
Happy Sista Devy
doaj +1 more source
The Effect of Temperature, Potato Varieties, and the Origin of Cyst on the Reproductive Biology of Globodera Rostochiensis [PDF]
Potato cyst nematode (Globodera rostochiensis [Wollenweber] Behrens) is a nematode species of worldwide regulatory concern. This nematode caused serious economic of potato losses in Indonesia.
Hartono, S. (Sedyo) +3 more
core +2 more sources

