Results 41 to 50 of about 7,375 (172)
MSI: A Mahalanobis‐Based Molecular Similarity Index for High‐Dimensional Embeddings
MSI pairs continuous Mol2Vec embeddings with a covariance‐aware Mahalanobis metric (dM, θM) to overcome the ranking ties and bit‐density bias of Tanimoto fingerprints. Across five reference compounds, MSI resolves more distinct neighbors than ECFP4 + Tanimoto and its geometry tracks HOMO–LUMO gaps in QM9, despite no electronic training.
Roberto Bernal‐Jaquez +4 more
wiley +1 more source
For generations, Mediterranean communities have used Lamiaceae or Labiatae plants like rosemary, thyme or mint to care for their health and to enrich their food. By bringing together dispersed knowledge from across the Mediterranean region, our review revealed the continuing relevance of Lamiaceae while also compiling past uses that may hold future ...
Fuencisla Cáceres +3 more
wiley +1 more source
FUNDAMENTO: Prática de exercício físico (EF) é eficiente no tratamento e na prevenção da hipertensão, associada à melhora do perfil lipídico e da função contrátil cardíaca.
Paulo Roberto Soares Filho +2 more
doaj
FUNDAMENTO: A disfunção erétil afeta um grande número de homens no mundo e os inibidores de PDE 5 (iPDE5) estão entre os principais métodos de tratamento desses pacientes.
Adauto Carvalho Silva +6 more
doaj +1 more source
ABSTRACT Background Seasonal influenza, especially in persons with underlying medical conditions, is a substantial global burden. Influenza vaccination effectiveness (VE) varies annually, requiring continuous evaluation due to evolving viruses and vaccination coverages. Our aim was to investigate influenza VE in preventing hospitalization for confirmed
Diana Toledo +50 more
wiley +1 more source
ABSTRACT Heat stress is an increasingly important challenge for the performance and welfare of equine athletes, particularly in competitions conducted across diverse climatic conditions. Understanding the genetic basis of performance responses to increasing thermal load is therefore essential to support robust genetic evaluation and sustainable ...
Mário Luiz Santana +1 more
wiley +1 more source
Abstract Long COVID (post‐acute sequelae of SARS‐CoV‐2 infection) affects approximately 5%–30% of survivors and is characterized by persistent fatigue, dyspnea, exercise intolerance, and cognitive impairment. We evaluated the immunological effects of supervised exercise in adults with long COVID.
Nora García‐Alonso +3 more
wiley +1 more source
Objetivo: identificar alterações cardiovasculares e pulmonares em pacientes em hemodiálise, correlacionando-as aos aspectos socioeconômicos.Método: estudo transversal, realizado em um hospital universitário e em uma clínica de hemodiálise do Nordestedo ...
Maria Isabel da Conceição Dias Fernandes +5 more
doaj +3 more sources
Regulação neural do sistema cardiovascular:
Introdução. O sistema cardiovascular dispõe de mecanismos refinados de ajuste da pressão arterial, atuando momento a momento (controle neural) e em longo prazo (controle humoral). Objetivo. Descrever as estruturas bulbares moduladoras do sistema cardiovascular. Método. Foram revisados estudos referentes aocontrole neural da circulação pelo bulbo, entre
Vitor Engrácia Valenti +3 more
openaire +1 more source
Combining PTP1B inhibitors of distinct kinetic mechanisms determines their pharmacological outcome. Integrating enzyme kinetics, docking, molecular dynamics, and membrane‐permeability simulations, we show that mechanistically compatible pairs (competitive + competitive; uncompetitive + mixed) yield additivity, whereas competitive + uncompetitive ...
Jonathan Trapala +7 more
wiley +1 more source

