Results 41 to 50 of about 7,089 (171)

RECEPTORES b-ADRENÉRGICOS NO SISTEMA CARDIOVASCULAR

Medicina (Ribeirão Preto), 2006
Os receptores b-adrenérgicos (b-AR) integram um sistema proteico ternário: b-AR, proteína G de acoplamento e enzimas como a adenilato-ciclase (AC) que produz o 3´-5´monofosfato de adenosina (AMPc). O principal mecanismo de ação do AMPc é a ativação da proteína quinase A (PKA), capaz de fosforilar inúmeros substratos.
Mário A. Neto, Ricardo R . Rascado, Lusiane M. Bendhack   +2 more
openaire   +3 more sources

Probiotic Stability and Antihypertensive Activity of Peptides in Aguamiel Syrup‐Fortified Milk Protein Fermented by Lacticasebacillus rhamnosus GG

eFood, Volume 7, Issue 4, August 2026.
This study evaluates the impact of aguamiel syrup on a synbiotic fermented dairy product, focusing on antihypertensive peptide release and Lacticaseibacillus rhamnosus GG survival. While metabolic parameters remained unchanged, aguamiel syrup enhanced bioactive peptide production and antihypertensive activity (45.3%), suggesting its potential as a ...
Olvera‐Rosales Laura Berenice, Leonel‐Enríquez Jorge Eduardo, Pérez‐Escalante Emmanuel, Castañeda‐Ovando Araceli, Contreras‐López Elizabeth, Cruz‐Guerrero Alma Elizabeth, González‐Olivares Luis Guillermo   +6 more
wiley   +1 more source

Mortality trends for diabetes mellitus, hypertension and cardiovascular disease among people living with and without HIV in Brazil during the COVID‐19 pandemic, 2020–2022

HIV Medicine, Volume 27, Issue 8, Page 1265-1276, August 2026.
Abstract Introduction People living with HIV (PLWH) face an increasing burden of non‐AIDS‐related chronic conditions. However, how the COVID‐19 pandemic affected chronic disease‐related mortality in this population remains unclear. We assessed changes in mortality among PLWH in Brazil during the COVID‐19 pandemic.
Tatyellen Natasha da Costa Oliveira, Rodrigo C. Moreira, Luiz Max Carvalho, Flávio Codeço Coelho, Marcelo Ferreira da Costa Gomes, Leonardo S. Bastos, Laís Picinini Freitas, Antonio G. Pacheco   +7 more
wiley   +1 more source

Modeling Patterns of Population Exposure With a Multiscale Framework Utilizing LOTOS‐EUROS Chemical Transport Model, Mobility Surveys and Particulate Toxicity

GeoHealth, Volume 10, Issue 7, July 2026.
Abstract The present study proposes a high‐resolution, multi‐component framework to estimate human exposure to air pollution in tropical urban environments, addressing complex topography and limited historical mobility and exposure data. This framework is applied to the city of Medellín in the Aburrá Valley in Colombia. To assess population exposure to
Valeria Solórzano‐Araque, Andrés Yarce Botero, Jhon Edinson Hinestroza‐Ramirez, Fernando Fernandez‐Restrepo, Sebastian Carmona Estrada, Pablo Alberto Osorio‐Marulanda, Lisseth Cruz‐Ruiz, Santiago Isaza‐Cadavid, O. L. Quintero   +8 more
wiley   +1 more source

Efeito do vinho tinto associado ao exercício físico no sistema cardiovascular de ratos espontaneamente hipertensos

Arquivos Brasileiros de Cardiologia, 2011
FUNDAMENTO: Prática de exercício físico (EF) é eficiente no tratamento e na prevenção da hipertensão, associada à melhora do perfil lipídico e da função contrátil cardíaca.
Paulo Roberto Soares Filho, Iran Castro, Adriene Stahlschmidt   +2 more
doaj  

Repercussão cardiovascular, com e sem álcool, do carbonato de lodenafila, um novo inibidor da PDE5 Repercusión cardiovascular, con y sin alcohol, del carbonato de lodenafila, un nuevo inhibidor de la PDE5 Cardiovascular repercussion of lodenafil carbonate, a new PDE5 inhibitor, with and without alcohol consumption

Arquivos Brasileiros de Cardiologia, 2010
FUNDAMENTO: A disfunção erétil afeta um grande número de homens no mundo e os inibidores de PDE 5 (iPDE5) estão entre os principais métodos de tratamento desses pacientes.
Adauto Carvalho Silva, Odaly Toffoletto, Luiz Antonio Galvão Lucio, Paula Ferreira dos Santos, Jorge Barros Afiune, João Massud Filho, Sergio Tufik   +6 more
doaj   +1 more source

Sources of Variation in Fecal Haptoglobin in a Population of Wild Capuchin Monkeys (Cebus imitator)

American Journal of Primatology, Volume 88, Issue 6, June 2026.
Fecal haptoglobin values show significant seasonal variation in wild capuchin monkeys. Values are highest, and most variable in the early‐mid dry season, when fruit is typically scarce and water sources are standing pools, which can accumulate pathogens.
Raquel Hernández‐Rojas, Hadjira Hamou, Ronald Lopez Navarro, Katharine M. Jack, Fernando A. Campos, Amanda D. Melin, James P. Higham   +6 more
wiley   +1 more source

Redirecting Alzheimer's disease therapeutics: Multitarget drugs and complementary non‐pharmacological strategies

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder driven by intersecting pathological processes. Persistent attrition in AD drug‐development pipelines highlights the limited clinical impact of single‐target therapies and has increased interest in multi‐target approaches acting on shared biological hubs.
Humberto Martínez‐Orozco, Jesús Andrade‐Guerrero, Nelly Jovana Pastén‐Castrejón, Chryslaine Rodríguez‐Tanty, Sofía Y Diaz‐Miranda   +4 more
wiley   +1 more source

MyoRep: A Novel Reporter System to Detect Early Muscle Atrophy In Vitro and In Vivo

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Muscle atrophy occurs during physiological (i.e., fasting) and pathological conditions (i.e., cancer) and anticipates death. Since not all patients will undergo muscle wasting, it would be highly useful to identify them soon to intervene early.
Andrea D. Re Cecconi, Nicoletta Rizzi, Mara Barone, Federica Palo, Martina Lunardi, Mara Forti, Adriana Maggi, Paolo Ciana, Giulia Terribile, Michela Chiappa, Lorena Zentilin, Rosanna Piccirillo   +11 more
wiley   +1 more source

Alterações cardiovasculares e pulmonares em pacientes submetidos à hemodiálise [Cardiovascular and pulmonary changes in patients undergoing hemodialysis] [Alteraciones cardiovasculares y pulmonares en pacientes sometidos a hemodiálisis]

Revista Enfermagem UERJ, 2016
Objetivo: identificar alterações cardiovasculares e pulmonares em pacientes em hemodiálise, correlacionando-as aos aspectos socioeconômicos.Método: estudo transversal, realizado em um hospital universitário e em uma clínica de hemodiálise do Nordestedo ...
Maria Isabel da Conceição Dias Fernandes, Cyndi Fernandes Lima, Cecília Maria Farias de Queiroz Frazão, Millena Freire Delgado, Marilia Gabriela Azevedo Araujio, Ana Luisa Brandão de Carvalho Lira   +5 more
doaj   +3 more sources