Results 161 to 170 of about 1,422 (188)
The Determinants of Negotiated Pharmaceutical Prices
ABSTRACT We focus on the determinants of pharmaceutical drug prices. Using data from the Brazilian pharmaceutical market, we find large variations in drug prices across buyers, drug classes, and time periods. Our estimation results provide evidence that transaction‐specific determinants between buyers and sellers (e.g., transaction volume, buyer's ...
Ralph B. Siebert +2 more
wiley +1 more source
Shaping future forests: how can ecophysiology support climate‐smart forest management?
Summary Climate change, particularly the associated increase in extreme events and disturbances, threatens the numerous environmental, social, and economic benefits that forests provide, both locally and globally. Heat and drought pose significant risks to forest ecosystems; the anticipated future climate is expected to exacerbate this trend ...
Arthur Gessler +18 more
wiley +1 more source
Can species adapt to drought using multiple strategies? Lessons from the California poppy
Summary Plants can escape drought by completing life cycles early, tolerate drought by increasing physiological limits, or avoid drought stress by obtaining or using water more efficiently. It remains unclear whether strategies vary within species across their distributional ranges due to trade‐offs, and whether species can exhibit plasticity in ...
Stuart T. Schwab +7 more
wiley +1 more source
Summary The study of seasonal xylem hydraulics has predominantly focused on embolism‐induced losses, whereas growth‐driven increases in hydraulic capacity have received little attention. We assessed the intra‐annual dynamics of xylem formation and gain of conductivity in the current‐year ring of three species with contrasting tree‐ring structure ...
Laura Fernández‐de‐Uña +4 more
wiley +1 more source
Vernalization regulatory network identifies potential novel functions for genes in the HvVRN2 locus
Summary Flowering is controlled by environmental and genetic factors. Vernalization requirement in barley (Hordeum vulgare L.) is determined by the allele in HvVRN1 and the presence of locus HvVRN2, which consists of two zinc‐finger and CONSTANS‐like domains (ZCCT) genes: HvVRN2a and HvVRN2b.
Francesc Montardit‐Tarda +6 more
wiley +1 more source
Ecological change may be a common initiator of evolutionary pollinator shifts
Summary Although evolutionary pollinator shifts are accepted as major sources of floral and species diversity in angiosperms, the mechanisms triggering pollinator shifts remain largely unexplored. In 1970, Stebbins proposed that ecological change may be a common initiator of evolutionary pollinator shifts, but empirical tests of Stebbins' hypothesis ...
Agnes S. Dellinger
wiley +1 more source
Somatic genome‐doubling is the most parsimonious route to allopolyploidy
Summary The origin of a polyploid can hinge on a single errant cell division, a mistake in the cell cycle that leads to genome‐doubling and re‐writes the rules of chromosome pairing and segregation. In plants, the evolutionary significance of these errors is magnified by lack of an early sequestered germline, meaning somatic mutations can be heritable.
Robin Burns +2 more
wiley +1 more source
Abstract figure legend Circulating extracellular vesicles (EVs) derived from acebuche (ACE) oil‐ and extra virgin olive oil (EVOO)‐fed mice modulate nitric oxide (NO) metabolism in the retinal pigment epithelial cell line (ARPE19) with a hypertensive phenotype induced by angiotensin II (AngII).
Álvaro Santana‐Garrido +6 more
wiley +1 more source
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