ABSTRACT We present the first x‐ray crystallographic structural evidence of an archaeal DNA ligase showing the AMP covalent adduct together with further cofactor hydrolysis, capturing a transient intermediary in the first step of the ligation reaction, triggered by the pyrophosphate hydrolysis.
A. X. Quintana‐Armas +3 more
wiley +1 more source
Estimation of care costs for individuals with cystic fibrosis at a referral center: cohort study, Salvador, 2005-2022. [PDF]
Costa JCB, Sorte NCAB, D'Souza EL.
europepmc +1 more source
Reconstruction techniques in nuclear medicine time-of-flight PET [PDF]
Vandenberghe, Stefaan
core +1 more source
When Public Health Becomes the Weapon: Current and Prospective Consequences of the Genocide in Gaza
ABSTRACT Catastrophic humanitarian conditions during the 2023–2025 genocide in Gaza have caused a public health crisis of exceptional magnitude. This article summarizes key short‐ and long‐term health consequences for Gaza's civilian population and outlines priorities for recovery.
Therese Alexandra Evald +19 more
wiley +1 more source
In which stage of the nursing process is ultrasonography used? [PDF]
Moraes VM +3 more
europepmc +1 more source
First continental‐scale synthesis of hygropetric beetle diversity and distribution across Neotropical highlands. Climatic and topographic gradients structure regional assemblages and niche overlap. Ecological convergence suggests adaptation to similar conditions across disjunct regions.
Janderson Batista Rodrigues Alencar +4 more
wiley +1 more source
Healthcare stakeholders' perspectives on coordinating cancer diagnosis in Chile, Colombia, and Ecuador. [PDF]
Oturai O +7 more
europepmc +1 more source
Innovation Ecosystems in Catalonia: Exploring Location Patterns of High‐Tech Firms
ABSTRACT This paper analyses high‐tech firms' location determinants in Catalonia, Spain, using 2010–2019 firm data, and spatial models to assess spillover and industry‐specific factor effects. Results show that high‐tech firms, especially in services, are clustered in busy, wealthy cities with strong innovation hubs, while non‐high‐tech firms prefer ...
Keli Araujo‐Rocha +1 more
wiley +1 more source
Geographic disparities and temporal trends regarding access to cancer treatment: a spatial analysis, Brazil, 2015-2022. [PDF]
Sousa EL +5 more
europepmc +1 more source
Da Vinci's mischief: xylem conduits in the stems of woody plants do not furcate
Summary The hydraulic architecture of plants is often modeled as a ‘furcating’ network, in which xylem conduits proliferate in number toward the stem apex, analogous to animal circulatory systems. Yet whether furcation actually occurs within woody stems remains untested, despite major implications for carbon costs and hydraulic efficiency.
Gilberto Alemán‐Sancheschúlz +4 more
wiley +1 more source

