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SISTER CHROMATID EXCHANGE FORMATION

Annual Review of Genetics, 1981
INTRODUCTION 11 INFORMATION ABOUT CHROMOSOME ORGANIZATION PROVIDED BY SCE ANALYSIS 12 SCE INDUCTION 15 SeE Induction by Diff erent Types of DNA Damage 16 Duration of the SCE Response 22 Modulation of the seE Response 23 CORRELATES OF SCEs ........
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Analysis of Sister‐Chromatid Exchanges

Current Protocols in Human Genetics, 1994
AbstractTwo requirements for the cytogenetic analysis of sister‐chromatid exchanges (SCEs) in somatic cells are (1) a population of actively proliferating cells that will provide an adequate number of metaphases and (2) sister chromatids that in some way are differentially labeled or stained in the metaphases.
J, German, B, Alhadeff
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Sister chromatid exchanges and heterochromatin

Human Genetics, 1981
The inter- and intrachromosomal distribution patterns of SCEs obtained with or without mutagen treatment are reviewed and compared, with each other as to their relation to heterochromatin and with the distribution patterns of chromatid aberrations that occurred either "spontaneously" in chromosomes of repair-defective human syndromes or after treatment
I, Schubert, R, Rieger
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Sister-Chromatid Exchanges

2007
The sister chromatid exchange (SCE) test is a relatively simple assay, sensitive to most mutagenic compounds. Its major disadvantage is that in order to detect SCEs cells must be either treated with the label for one round of replication prior to treatment with the mutagen studied or treated simultaneously, but fixed and harvested following two rounds ...
Andrzej Wojcik, Günter Obe
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Sister chromatid exchange in newborns

Human Genetics, 1981
Sister chromatid exchanges (SCE) were analyzed in the cord and postnatal blood of controlled groups of low and high birth weight infants to detect possible associations between abnormal birth weight and SCE frequency. Structural chromosome aberration rates had previously been evaluated for all infants, and possible correlations between aberration and ...
N H, Hatcher, E B, Hook
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Sister chromatid exchanges in isolabeling

Experimental Cell Research, 1974
Isolabeling observed by autoradiography in sister chromatids at the second or later metaphases after incorporation of 3H-thymidine has sometimes been ascribed to an exchange between the multiple DNA duplexes in polynemic sister chromatids. An analysis reported here on the frequency and size of isolabeled regions in chromosomes of the rat kangaroo shows
D A, Gibson, D M, Prescott
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Sister Chromatid Exchanges*

2005
This article is a revision of the first print edition article by Ann D Mitchell, volume 3, pp 144–146, © 1998, Elsevier Inc. who has now sadly deceased.
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Sister chromatid exchanges in barley

Theoretical and Applied Genetics, 1980
A mean frequency of 20.6 sister chromatid exchanges (SCEs) per cell has been observed in a reconstructed karyotype of Hordeum vulgare by application of the FPG technique after unifilar incorporation of BrdU into chromosomes. The involvement in SCEs of the 48 segments into which the chromosome set had been subdivided was, with a single deviation, length
I, Schubert   +4 more
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Sister chromatid exchange in Waldenström's macroglobulinemia

Cancer Genetics and Cytogenetics, 1993
Results on sister chromatid exchange (SCE) frequency and interchromosomal distribution in bone marrow and peripheral blood cultures from patients with Waldenström's macroglobulinemia are reported. PHA-stimulated bone marrow cultures showed increased SCE frequencies in all 12 patients examined.
Carbone P.   +3 more
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Analysis for Sister Chromatid Exchange

2022
Sister chromatid exchange (SCE) is the exchange event of genetic material between two identical sister chromatid. Elevation of SCE frequency is considered as a result of replication stress from genetic defects, ROS stress, and genomic damages. SCE staining needs extra processes compared to regular Giemsa staining.
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