Results 41 to 50 of about 2,631,711 (310)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
Service optimization for bus corridors with short-turn strategies and variable vehicle size
, 1998 An optimization framework for intermediate-level planning of bus operations on a given corridor is presented. Service patterns over different operation periods, which include short-turn strategies (full-length and short-turn line) and variable vehicle ...
SITE, P D +5 more
core +1 more source
Geomatics, Natural Hazards & RiskThis study evaluates the seismic impact of the Bukit Timah granite massif in Singapore, emphasizing the role of granite weathering in local site effects.
Farkhod Hakimov +6 more
doaj +1 more source
Sensors, 2010 Over the last few years, the analysis of seismic noise recorded by two dimensional arrays has been confirmed to be capable of deriving the subsoil shear-wave velocity structure down to several hundred meters depth.
Matteo Picozzi +6 more
doaj +1 more source
Cooperative effects on the formation of intercalation sites [PDF]
Nucleic Acids Research, 2004 Daunomycin is one of the most important agents used in anticancer chemotherapy. It interacts with DNA through intercalation of its planar chromophore between successive base pairs. The effect of intercalation on structure, dynamics and energetics is the topic of a wealth of scientific studies. In the present study, we report a computational examination
Michael, Trieb +4 more
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman +7 more
wiley +1 more source
Ex-ante assessment of urban freight transport policies
, 2010 Many city public authorities have implemented measures to alleviate the negative effects of freight transport in urban areas, but these have often proved ineffective.
Delle Site, P. +13 more
core +1 more source
Shallow Shear-Wave Velocity Beneath Jakarta, Indonesia Revealed by Body-Wave Polarization Analysis
Geosciences, 2019 Noting the importance of evaluating near-surface geology in earthquake risk assessment, we explored the application to the Jakarta Basin of a relatively new and simple technique to map shallow seismic structure using body-wave polarization.
Rexha Verdhora Ry +2 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm +11 more
wiley +1 more source