Site-Specific PEGylation at Residue 86 Improves Pharmacokinetic Properties of Interferon α-2b. [PDF]
Alboshokeh MA +5 more
europepmc +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Optimization of the External Directing Group Depending on the Substrates for the Regioselective C-H Alkenylation of Phenyl Ethers. [PDF]
Yano K, Sawada D.
europepmc +1 more source
Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner +6 more
wiley +1 more source
Structural and dynamic properties of IL1 receptors. [PDF]
Zhukova JV, Lopatnikova JA, Sennikov SV.
europepmc +1 more source
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah +8 more
wiley +1 more source
Mesenchymal Stem Cell-Derived Exosomes: A Promising Therapeutic Strategy for Spinal Cord Injury. [PDF]
Li X +5 more
europepmc +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
On the Origin of Substrate Specificity of Enzymes from the Amidohydrolase Superfamily. [PDF]
Drexler L +3 more
europepmc +1 more source
Universal role of quinones in natural and artificial photosynthetic systems: overview from chemical properties to biological importance. [PDF]
Łazicka M, Garstka M.
europepmc +1 more source

