Results 151 to 160 of about 1,087,035 (252)

Socioeconomic Disparities in Outcomes After Primary Total Hip Arthroplasty: A Propensity-Matched Multi-Institutional Study. [PDF]

Arthroplast Today
Artus K, Anand L, Yanoff Z, Shoap S.
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Comparative Diagnostic Performance of Cone Beam Computed Tomography and Dual-Energy X-Ray Absorptiometry for Low Bone Density Assessment. A Systematic Review and Meta-Analysis. [PDF]

Clin Exp Dent Res
Alrashidi M, Elbishari H, Aljanahi M, Amir-Rad F, Chaudhry J, Atieh M.   +5 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Differential Dose-Response Behavioural Profiles of Diazepam, Zolpidem and Indiplon in a Two-Trial Y-Maze Paradigm in Rats. [PDF]

Pharmaceuticals (Basel)
Moraru MV, Coman OA, Zugravu A, Stoleru S, Ghiță CIV, Costescu M, Poenaru E, Dragomir AF, Barbu AC, Lunca DC, Stoian A, Jafal MN, Stoleru CM, Fulga I.   +13 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Pan-European maps and models of current and future tree species distributions and their growth potential. [PDF]

Data Brief
Wöhlbrandt A, Onay A, Bachmann-Gigl U, Falk W, Temperli C, Aspalter S, Chakraborty D, Schüler S, Breidenbach J, Fridman J, Isaac-Renton M, Šebeň V, Skudnik M, Zlatanov T, Thom D, Thurm EA.   +15 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Comparison of the Cortical Activity Index and Bispectral Index During General Anesthesia: A Prospective Observational Study. [PDF]

Medicina (Kaunas)
Sung TY, Lee S, Cho CK, Jung JY, Oh H, Hwang S, Kwon W.   +6 more
europepmc   +1 more source