Results 71 to 80 of about 24,137,124 (342)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Re: Final site investigation reports, Former Lincoln Air Force Base, Atlass Missile Site 12 (Brainard, Nebraska) and Atlas Missile Site 10 (Bradshaw, Nebraska)

open access: yes, 2021
. ~-. 'StATE OF NEBRASKA E. Benjamin Nelson Go verno r December 19, 1997 DEPARTMENT OF ENVIRONMENTAL QUAUTY Randolph Wood Director Suite 400 , The Atrium 1200 'N' Street p.O. Box98922 Linco ln, Nebraska 68509-8922 Phone (402) 471 -2186 Mr.
Nebraska. Department of Environmental Quality
core  

ANNUAL TRANSPORTATION REPORT FY 2007, Radioactive Waste Shipments to and from the Nevada Test Site (NTS) [PDF]

open access: yes, 2007
In February 1997, the U.S. Department of Energy, Nevada Operations Office (now known as the Nevada Site Office) issued the Mitigation Action Plan which addressed potential impacts described in the “Final Environmental Impact Statement for the Nevada Test
OFFICE, DOE NNSA NEVADA SITE
core   +1 more source

Carbapenem Resistance in Three Hospitals in India: A Need for Strengthening Infection Prevention and Control Practices

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology
Background: Carbapenem-resistant (CR) organisms (CROs) pose a serious public health threat. We examined the burden of CRO colonization, the proportion of CROs among clinical isolates, and infection prevention and control (IPC) practices in three ...
Bharat Randive   +15 more
doaj   +1 more source

Practice structure and quality improvement activities among emergency departments in the Emergency Quality (E‐QUAL) Network

open access: yesJournal of the American College of Emergency Physicians Open, 2020
Objectives Little academic investigation has been done to describe emergency department (ED) practice structure and quality improvement activities. Our objective was to describe staffing, payment mechanisms, and quality improvement activities among EDs ...
Carl T. Berdahl   +7 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Good Laboratory Practice in Analytical Chemistry with Modern Laboratory Management

open access: yesProceedings, 2020
Analytical chemistry is experiencing dramatic, turbulent change beyond laboratory and laboratory management control. Technological innovations, staffing demographics, new business models, automation, industry consolidation, society, regulatory ...
Jacobus (Koos) Frederick van Staden
doaj   +1 more source

Choosing the “Rightweight” Model for Web Site Quality Evaluation [PDF]

open access: yes, 2003
One of the most critical decisions in a quality evaluation project is to establish the level at which to analyse the characteristics of the Web sites. This choice should be driven by the underlying goals of the evaluation. Scalability and flexibility are thus desiderable features of the models used to evaluate the quality of a Web site.
Mich, Luisa   +3 more
openaire   +3 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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