Results 71 to 80 of about 2,905,224 (291)

Conversion Rate Optimization through Evolutionary Computation

, 2017
Conversion optimization means designing a web interface so that as many users as possible take a desired action on it, such as register or purchase.
Brundage, Myles, Cordell, Ron, Dean, Randy, Epstein, Jonathan, Iscoe, Neil, Lamba, Gurmeet, Miikkulainen, Risto, Nazari, Sam, Schoolland, Cory, Shagrin, Aaron   +9 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

ANALYSIS OF SOIL FERTILITY TESTING PROCEDURES USING UNIFORM, TOPOGRAPHICAL AND OTHER SITE-SPECIFIC METHODS [PDF]

This study summarizes an analysis of uniform, topographical and other site-specific soil fertility testing procedures based on observations of various crops at various locations in North Dakota and one location in Minnesota for 2001 through 2004. Results
Aakre, Dwight G., Haugen, Ronald H.
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

First astronomical preselecting site in the Beni Mellal region: On the use of satellite data

Journal of Applied Surfaces and Interfaces, 2017
In this paper we use satellite meteorological and geophysical data to compare three new sites to the Oukaimeden Observatory (J43) located in the Atlas mountains (Morocco). The Three other sites are located in Beni Mellal mountains.
Z. Ihsane, E.A. Siher, A. Salhi, C. Satif   +3 more
doaj  

Facilitating Electroactive Site Density Determination during Fuel‐Cell Testing

ChemElectroChem
The increase in performance and durability the platinum group metal (PGM)‐free catalysts makes them a viable alternative to PGM catalysts at the cathodes of low‐temperature fuel cells.
Rifael Z. Snitkoff‐Sol, Lior Elbaz
doaj   +1 more source

Optimizing crop loading of apples and pears - results 2004-2006 (foliar fertilizers, thinning) [PDF]

, 2008
Main topics of the research-project FuE 03OE088 of “Bundesprogramm Ökologischer Landbau” (30.04.2004-31.12.2006) were the testing of foliar fertilizers in organic apples and pears, optimizing lime sulphur for blossom thinning, looking for alternatives ...
Eis, B., Fieger-Metag, N., Pfeiffer, B., Zimmer, J.   +3 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source