Results 221 to 230 of about 10,087,786 (356)

Genome-Wide 6mA Map Unveils Epigenetic Adaptation in Deep-Sea Limpet. [PDF]

open access: yesEcol Evol
Chen C   +9 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Real-World Estimates of HIV Incidence From Sexual Health Clinic EMRs: Feasibility, Limitations, and Implications for Surveillance. [PDF]

open access: yesJ Acquir Immune Defic Syndr
Fischer Walker C   +19 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Catch basin larvicide treatments impact adult mosquito West Nile virus vector species in metropolitan Milwaukee, WI, U.S.A. [PDF]

open access: yesPLoS One
Johnson HE   +6 more
europepmc   +1 more source

IDENTIFICATION AND AMS RADIOCARBON DATING OF WOOD, ZEA MAYS COB, AND BONE FROM THE STAR CEILING CAVE SITE NEAR CUBA, NEW MEXICO AND ZEA MAYS COB MORPHOMETRICS

open access: green, 2011
Puseman, Kathryn, AUTHOR (PaleoResearch Institute); Cummings, Linda Scott, AUTHOR (PaleoResearch Institute); Yost, Chad, AUTHOR (PaleoResearch Institute)
openalex   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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