Results 291 to 300 of about 12,868,149 (415)

Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations

FEBS Open Bio, EarlyView.
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo, Klaudia Jaczynska, Christian Rosenmund   +2 more
wiley   +1 more source

Factors contributing to the abundance and spatial distribution of the invasive intermediate host snail (Pseudosuccinea columella) in uMgungundlovu district, KwaZulu-Natal, South Africa. [PDF]

BMC Vet Res
Hadebe MI, Manyangadze T, Kalinda C, Chimbari MJ.   +3 more
europepmc   +1 more source

The Medora site, West Baton Rouge Parish, Louisiana / by George I. Quimby, Curator of Exhibits, Dept. of Anthropology

, 1951
George I. Quimby
openalex   +2 more sources

The functional universe of membrane contact sites

Nature reviews. Molecular cell biology, 2019
W. Prinz, Alexandre Toulmay, T. Balla
semanticscholar   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

Distinct transmission sites within a synapse for strengthening and homeostasis. [PDF]

Sci Adv
Yang Y, Wong MH, Huang X, Chiu DN, Liu YZ, Prabakaran V, Imran A, Panzeri E, Chen Y, Huguet P, Kunisky A, Ho J, Dong Y, Carter BC, Xu W, Schlüter OM.   +15 more
europepmc   +1 more source

Studies of the site and the mode of action of 3-dimethylamino-1, 1-di (2'-thienyl) but-1-ene: HCl (Ohton) on the central nervous system of cats

, 1957
茂 山本
openalex   +2 more sources

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source

Info site

, 2011
openaire   +4 more sources

DeepMethyGene: a deep-learning model to predict gene expression using DNA methylations. [PDF]

BMC Bioinformatics
Yan Y, Chai X, Liu J, Wang S, Li W, Huang T.   +5 more
europepmc   +1 more source