Results 311 to 320 of about 14,143,268 (384)

Genome-wide demethylation and targeted remethylation during metamorphosis in the jewel wasp Nasonia vitripennis. [PDF]

Epigenetics Chromatin
Thomas CL, Mallon EB.
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

MOF-based catalysts for sustainable biodiesel production: classification, performance, and advances from 2020 to 2025. [PDF]

RSC Adv
Keshta BE, Abdalla S, Tesnim D, Abou El-Reash YG, Al-Farraj ES, Shaban MM, El-Harairy A, El-Saeed HM, El-Harairy A, Shaban EA, Abou-Elyazed AS, Goda MN, Atwa EM, Keshta AE.   +13 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Uli-epic: profiling RNA modifications from ultra-low input samples. [PDF]

Genome Biol
He W, Xu C, Chen W, Jiang X, Wang Y, Peng Y, Chang S, Zhu W, Kang J, Hu L.   +9 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Interspecific interactions moderate direct effects of vegetation change resulting from prescribed fires. [PDF]

Sci Rep
Shastry VS, Conner LM, Morris G, Royle JA, Smith LL, Morin DJ.   +5 more
europepmc   +1 more source

Patient Experience of Presurgical Care for Carpal Tunnel Syndrome Across Treatment Sites in the Veterans Affairs Health System: A Qualitative Analysis. [PDF]

J Hand Surg Glob Online
Alessio D, Ortolan V, Harrod M, Sears ED.   +3 more
europepmc   +1 more source

Transcriptome-wide m6A landscape across diverse porcine tissues revealed by nanopore direct RNA sequencing. [PDF]

Front Genet
Liao Y, Ding Z, Chen X, Yin C, Yang B, Yang Q, Xing Y.   +6 more
europepmc   +1 more source