Results 101 to 110 of about 736,920 (303)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

Global, international, and intercultural competencies in a Trans-Atlantic and Pacific Project (TAPP) partnership

open access: yesJournal of Virtual Exchange
Virtual exchanges through the Trans-Atlantic and Pacific Project (TAPP) allow instructors to design collaborations that engage students in global, international, and intercultural (GII) competencies, which are increasingly emphasised through the ongoing ...
Ashleigh Petts   +1 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

“We Laugh Much More Together.” How Art Courses in School Facilitate Unintended Apprenticeship Between Artists and Educators

open access: yesNordic Studies in Education
This article explores how arts-based programs in Danish schools and daycare centers support educators’ professional development through collaboration with professional artists.
Maria Lyndgaard Petersen, Lene Tanggaard
doaj   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento   +3 more
wiley   +1 more source

Employee engagement in discussion: Goals, perspectives and recommendations

open access: yesJournal of Human Resource Management, 2017
This paper represents a summary of a debate on employee engagement that was conducted in a Business School setting. In this debate, representatives from key stakeholders group participated in this debate. The debate highlighted several critical concerns.
Debora Jeske   +3 more
doaj  

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani   +10 more
wiley   +1 more source

Extended Reality Applications in Environmental Education: A Field Learning Approach to Understanding Lake Ecosystems

open access: yesApplied Sciences
This study examines the design and pedagogical evaluation of Extended Reality (XR) applications, with a primary focus on location-based Augmented Reality (AR).
Athanasios Evagelou   +1 more
doaj   +1 more source

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