Results 41 to 50 of about 12,273 (251)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Analisis User Flow pada Website Pendidikan: Studi Kasus Website DKV UK Petra

open access: yesNirmana, 2022
User flow atau alur pengguna biasanya berbentuk diagram yang merupakan alur pergerakan yang dilalui oleh pengguna saat menggunakan sebuah produk. Produk dalam penelitian ini berarti website.
Ryan Pratama Sutanto
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Situs Inversus Totalis [PDF]

open access: yesMilitary Medicine, 2011
We present a case of situs inversus totalis. A 22-month-old infant presented with cyanosis, double-inlet left ventricle, severe pulmonary stenosis, and concern for underlying visceroatrial abnormalities. Chest (Fig. 1) and abdominal (Fig. 2) radiographs were obtained.
Paul J, Shogan, Les, Folio
openaire   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

The Effects of Google Word Coach Game and Vocabulary Mastery on Students’ Speaking Skill

open access: yesEthical Lingua: Journal of Language Teaching and Literature, 2020
The research aims to examine the effects of google word coach game and vocabulary mastery on students' speaking skills. This quasi-experimental study uses a 2x2 nonequivalent control group design with a factorial design carried out in four parallel ...
Suryadi Suryadi   +2 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Manajemen Mutu Layanan Ta’lim Quran lil Aulad (TQA) di Yayasan Team Tadarus “AMM” Yogyakarta

open access: yesJurnal Nuansa Akademik, 2020
Qualitative research on the quality of Quran education services has a specificity according to the character of the material that prioritizes recitation and reading recitation, especially for TQA education organized by the Tadarus Team Foundation for the
Supriati H. Rahayu   +4 more
doaj   +1 more source

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