Results 101 to 110 of about 228,179 (253)
SEC Mediates m6A Deposition and Transcription Pause Release to Drive Cell Identity Transition
Advanced Science, EarlyView.The SEC promotes cell identity transitions by facilitating transcription pause release at key identity‐associated genes, including Klf4 and Myc during iPSC reprogramming and Nes and Tubb3 during ESC‐to‐neuroectodermal differentiation. During early iPSC reprogramming, this function additionally involves cooperation with METTL3‐associated m6A regulation.
Zhijing Zhang +9 more
wiley +1 more source
From Artificial to Embodied and Physical Intelligence in Smart Manufacturing
Advanced Science, EarlyView.Smart manufacturing is reframed through complementary artificial, embodied, and physical intelligence, spanning computational reasoning, perception‐action coupling, and material‐level adaptation. Their integration across design, fabrication, operation, and maintenance reveals how intelligence can be co‐designed across algorithms, embodied agents, and ...
Kang Wang +9 more
wiley +1 more source
Advanced Science, EarlyView.Subcellular spatial transcriptomics enables high‐resolution mapping of gene expression within tissues, but accurate cell segmentation is essential for assigning transcripts to individual cells. We present SpaCut, a deep learning framework that integrates transcriptomic features with nucleus‐guided morphological information to precisely delineate cell ...
Yongheng Li, Fangfang Zhu, Wenwen Min
wiley +1 more source
Advanced Science, EarlyView.Efoba, a novel bioactive component derived from aged garlic, confers neuroprotection against intracerebral hemorrhage. It acts on microglia to suppress CTSC release, inhibits NET‐mediated neural injury, and blocks pathological microglia‐neutrophil crosstalk. This study provides a highly promising lead compound for hemorrhagic‐stroke therapy.
Junjun Meng +7 more
wiley +1 more source
Radical, Not Ionic: The Mechanochemical Zincke Nitration of Phenols
Angewandte Chemie, EarlyView.Mechanochemistry recasts the classical Zincke nitration as an open‐shell process. Liquid‐assisted vibrational milling of phenols with in situ HNO2 delivers direct and ipso nitration across 50 substrates, while atmosphere, NOx‐transfer, EPR and DFT evidence expose a phenoxyl‐radical/NO2 manifold underlying this historically ionic transformation ...
Roberto Scipione +7 more
wiley +2 more sources
Molecular Analysis In The Management Of Congenital Adrenal Hyperplasia (CAH) And Ambiguous Genitalia. [PDF]
, 2002 Patients presenting with ambiguous genitalia (AG) often pose a dilemma to the attending clinicians with regard to sex ...
Muhamad, Y.K. +6 more
core +1 more source
Artificial Intelligence for Fluorite Ferroelectric Materials: From Discovery to Optimization
Advanced Electronic Materials, EarlyView.Artificial intelligence accelerates the discovery and optimization of HfO2‐based fluorite ferroelectrics by linking synthesis, structure, properties, and device performance. Machine learning, deep‐learning analysis, and AI‐driven atomistic modeling enable predictive design, dopant screening, and closed‐loop optimization toward next‐generation ...
Faizan Ali +3 more
wiley +1 more source
Interfacial Water‐Networks Regulate the Anodic Stability of Carbon Electrodes
Angewandte Chemie, EarlyView.The hydrogen‐bonding networks of interfacial water serve as active stability descriptors for carbon anodes: disrupted water‐networks accelerate anodic carbon corrosion, whereas strongly hydrogen‐bonded networks suppress it. This principle enables extension of the stable potential window of carbon electrodes through ionomer‐defined interfaces, as ...
Junsic Cho +12 more
wiley +2 more sources
, 2018 Belakangan ini, publik dihebohkan dengan insiden vandalisme situs Majapahit. Melalui media sosial, seorang warga Mojokerto mengunggah sebuah foto yang menunjukkan aktivitas penjarahan batu bata dari struktur bangunan bersejarah di Desa Kumitir, Kecamatan
Luthfy, Riza Multazam
core