Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Pendekatan Servqual-lean Six Sigma Menggunakan Diagram Kontrol T2 Hotelling Untuk Meningkatkan Kualitas Pelayanan Pendidikan (Studi Kasus Di Jurusan Statistika Universitas Diponegoro) [PDF]
, 2015 Measurement the service of quality has an important role in improving and evaluating the performance of a service process. Measuring the service of quality is not as easy as measuring the goods quality, because the assessment service is subjective ...
Darwati, L. (Lulus) +2 more
core
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
ON THE STATISTICAL CONTROL OF THE RACING PROCESS BRACKET CENTER SUPPORT USING THE SIGMA SIX METHOD [PDF]
Fiabilitate şi Durabilitate, 2018 By applying the Six Sigma method, it is intended to calculate the capability reinforcement bracket support bracket process to see if it is stable and to see if the degree of dispersion of values is close to the limits of a normal ...
Ancuţa BĂLTEANU +2 more
doaj
A Preliminary Study of Applying Lean Six Sigma Methods to Machine Tool Measurement [PDF]
, 2015 Many manufacturers aim to increase their levels of high-quality production in order to improve their market competitiveness. Continuous improvement of maintenance strategies is a key factor to be capable of delivering high quality products and services ...
Fletcher, Simon +2 more
core
A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions
Advanced Engineering Materials, EarlyView.This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice +2 more
wiley +1 more source
Aplikasi Six Sigma Dmaic sebagai Metode Pengendalian dan Perbaikan Kualitas Produk Bedside Cabinet Skn 04-03abs pada PT. Sarandi Karya Nugraha [PDF]
, 2016 (APPLICATION OF SIX SIGMA DMAIC AS A CONTROL AND QUALITY IMPROVEMENT METHODS FOR SKN 04-03ABS BEDSIDE CABINET PRODUCT IN PT. SARANDI KARYA NUGRAHA)The main factors to achieve business success in global competition is quality.
Arvianto, A. (Ary) +1 more
core
Advanced Engineering Materials, EarlyView.This study investigates innovative thermoreversible hydrogels derived from S53P4 bioactive glass extracts to aid in the healing of infected diabetic foot wounds. These injectable gels, which gel at body temperature, release beneficial ions and remain stable over time.
Marian G. Vargas Guerrero +9 more
wiley +1 more source
An assessment of the challenges and successes experienced when implementing the six sigma methodology in Continental Tyre South Africa [PDF]
, 2006 Globalisation has opened up international markets for South African companies, but has also introduced competition in the domestic market. As a result, South African organisations are forced to attain global efficiency levels if they are to compete on ...
Kanakana, Mukundeleli Grace
core +1 more source