Results 21 to 30 of about 707,003 (287)

Six Sigma: Main Metrics and R Based Software for Training Purposes and Practical Industrial Quality Control

open access: yesKvalita Inovácia Prosperita, 2019
Purpose: To clarify the different types of data likely to occur in any service or industrial process, the main applicable statistics for each type of data and the Six Sigma metrics that allow characterising and benchmarking organisational processes ...
Ana Rita Costa   +3 more
doaj   +1 more source

Green Lean Six Sigma implementation framework: a case of reducing graphite and dust pollution

open access: yesInternational Journal of Sustainable Engineering, 2020
Modern organisations are in search of initiatives which will enable them to be sustainable as well as gain a competitive advantage. Lean, Six Sigma and Green initiatives are some of the widely used tools which aid the organisation to be sustainable ...
Michael Sony, Subhash Naik
doaj   +1 more source

New Paradigm of Lean Six Sigma in the 4th Industrial Revolution Era

open access: yesKvalita Inovácia Prosperita, 2020
Purpose: In early 2000s Six Sigma and Lean were combined into Lean Six Sigma (LSS), which has been one of the major strategic quality initiatives all over the world.
Sung Hyun Park   +2 more
doaj   +1 more source

A Lean Six Sigma framework to enhance the competitiveness in selected automotive component manufacturing organisations

open access: yesSouth African Journal of Economic and Management Sciences, 2018
Background: Currently, globalisation, economic uncertainty and fluctuating market demands prompt leaders all over the world to improve their operations and to enhance innovations in processes, products and services in a very reactive manner.
Raveen Rathilall, Shalini Singh
doaj   +1 more source

LEAN SIX SIGMA: LONG TERM APPROACH FOR GROWTH AND COMPETITIVENESS IN ROMANIA [PDF]

open access: yesBusiness Excellence and Management, 2017
This paper investigates the benefits of Lean Six Sigma’s deploying in Romanian’s economy. After a brief introduction pointing out the advantages of Lean Six Sigma, Lean Six Sigma concept is introduced.
Alexandra Mirela Cristina MUNTEANU
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Using Lean Six Sigma techniques to improve efficiency in outpatient ophthalmology clinics

open access: yesBMC Health Services Research, 2021
Background Increasing patient numbers, complexity of patient management, and healthcare resource limitations have resulted in prolonged patient wait times, decreased quality of service, and decreased patient satisfaction in many outpatient services ...
Andrew W. Kam   +9 more
doaj   +1 more source

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