Results 171 to 180 of about 10,685,462 (289)

Recycled aggregate size effect on shear and tensile fracture toughness of SCB Eco-friendly cemented specimens. [PDF]

Sci Rep
Dolatshahi A, Arash M, Molladavoodi H.
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Theoretical Investigation of Quantum Size Effect on the Electronic Structure and Photoelectric Properties for Graphdiyne Nanotubes. [PDF]

Nanomaterials (Basel)
Zhang T, Wen H, Li Z, Zhao X, Wang X, Wang J.   +5 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The unit size effect on chocolate consumption: How to make consumers eat less? (The unit size effect on chocolate consumption). [PDF]

Heliyon
Kontor E, Soós M, Balsa-Budai N, Kovács S, Szakály Z.   +4 more
europepmc   +1 more source

Anisotropic Deformation Behavior and Indentation Size Effect of Monocrystalline BaF₂ Using Nanoindentation. [PDF]

Materials (Basel), 2023
Du G, Yang X, Deng J, Guo Y, Yao T, Li M, Geng R.   +6 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

The Size Effect on the Phase Transition and Dielectric Properties of Poly(vinylidene Fluoride) Ferroelectric Polymers. [PDF]

Polymers (Basel)
Zhao X, Yu M, Zhang X.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Size effect on thermal conductivity and stability of TiO₂/MWCNT-based hybrid nanofluids synthesized <i>via</i> probe ultrasonication. [PDF]

RSC Adv
Heshmatian S, Aligholami M, Shafiei S, Madiba IG, Azizi S, Hussein AA, Maaza M.   +6 more
europepmc   +1 more source