Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Accuracy and Interobserver Reliability of Preoperative Templating of the Tibial Component in Medial Unicompartmental Knee Replacement. [PDF]
Mashaly M, Akram RB, Krishnan H.
europepmc +1 more source
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Single-Molecule Microfluidics for Membrane Protein Biophysics. [PDF]
Krainer G.
europepmc +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Safety, Optimal Valve Therapy and Then Approach: We All Agree. [PDF]
Toubat O, Scheffel E, Ibrahim ME.
europepmc +1 more source
Stem design and sizing influence torsional periprosthetic fracture resistance of cemented stems in osteoporotic femoral models: a comparative biomechanical study. [PDF]
Hashimoto K +3 more
europepmc +1 more source
Cardiac CT Roadmap for Left Atrial Appendage Occlusion: From Planning to Strategy to Follow-Up. [PDF]
Meloni A +14 more
europepmc +1 more source
Integrated design for rural microgrids in Egypt incorporating hydrogen energy and vehicle-to-grid technology. [PDF]
Sayed MS, Alham MH, Ibrahim DK.
europepmc +1 more source

