Results 81 to 90 of about 52,777 (266)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Nature, 1945 IN his letter, Mr. J. Phelps1 refers to an interesting point in the manufacture of threepences, namely, their expansion in the coining press into dodecagonal steel collars. The fact that the corners of coins subsequent to 1940 are more rounded than are those of earlier ones seems to point to a change in the collars at about that date.
openaire +3 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
IEEE AccessThe increasing complexity of modern power distribution networks necessitates advanced strategies for reactive power compensation, particularly in capacitor placement and sizing.
Kwabena Addo +3 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
A study on the printability properties of alkali-sized recycled papers
Science and Engineering of Composite Materials, 2016 Recycled handsheets were prepared from old newspapers and old office papers with internal sizing applications of alkyl ketene dimer (AKD) emulsion at 0.5%, 1.0% and 1.5% addition levels as received basis.
Aydemir Cem
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Implantable Collamer Lens Procedure Planning: A Review of Global Approaches
Clinical OphthalmologyVance Thompson,1,2 Arthur B Cummings,3 Xiaoying Wang4– 6 1Vance Thompson Vision, Sioux Falls, SD, USA; 2Department of Ophthalmology, University of South Dakota Sanford School of Medicine, Vermillion, SD, USA; 3Wellington Eye Clinic, Dublin, Ireland; 4Eye
Thompson V, Cummings AB, Wang X
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Revista Facultad de Ingeniería Universidad de Antioquia, 2018 Despite the fact that solar photovoltaic (PV) water pumping systems, in particular, irrigation systems have been in use for more than 40 years, there remains a need for their improvement and development.
Bojan Ðurin +2 more
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