Results 121 to 130 of about 18,818 (197)

Sjögren's syndrome-focusassist: lymphocytic focus assessment in Sjögren's syndrome: a deep learning and spatial analysis approach. [PDF]

open access: yesDiagn Pathol
Zhang J   +14 more
europepmc   +1 more source

Beyond Glucocorticoids: The Current Landscape and Prospects for Treating Immune Checkpoint Inhibitor‐Induced Autoimmunity

open access: yesACR Open Rheumatology, Volume 8, Issue 8, August 2026.
The rapid integration of immune checkpoint inhibitors (ICIs) into standard oncology protocols has birthed a new frontier in clinical rheumatology: immune‐related adverse events (irAEs). By disrupting the programmed cell death‐1 (PD‐1)/PD‐L1 and cytotoxic T‐lymphocyte‐associated protein 4 (CTLA‐4) axes to restore antitumor T cell activity, these ...
Xizi Hu   +3 more
wiley   +1 more source

B‐Cell Depletion Relative to Tumor Necrosis Factor Inhibition Extends the Duration of Viral Shedding in COVID‐19 Among Autoimmune Disease Patients: A Matched Prospective Cohort Study

open access: yesACR Open Rheumatology, Volume 8, Issue 8, August 2026.
Objective To investigate SARS‐CoV‐2 viral shedding duration in autoimmune patients using B cell depleting (BCD) therapy or tumor necrosis factor inhibitors (TNFi) and immunocompetent comparators. Methods We conducted a matched cohort analysis among participants in POSITIVES, a prospective study enrolling outpatients with acute COVID‐19 within five days
Liya Sisay Getachew   +34 more
wiley   +1 more source

Targeting METTL3 Attenuates Thyroid Inflammatory Injury by Restoring Th17/Treg Balance through a YTHDC2‐m6A‐Dependent KDR/VEGFA Loop

open access: yesAdvanced Science, Volume 13, Issue 45, 13 August 2026.
METTL3‐mediated m6A modification stabilizes KDR/Kdr mRNA through YTHDC2, amplifying the VEGFA‐KDR feedback loop and disturbing Th17/Treg balance. This pathway promotes persistent inflammation and tissue damage in patients with AIT, and inhibiting the METTL3‐KDR axis effectively disrupts this circuit, alleviating thyroid tissue injury and disease ...
Qingyi Hu   +7 more
wiley   +1 more source

Shared gene signatures between rheumatoid arthritis and Sjögren's syndrome. [PDF]

open access: yesAm J Clin Exp Immunol
Li YF   +6 more
europepmc   +1 more source

Overlap of Primary Biliary Cholangitis and Systemic Sclerosis: A Case of Reynolds Syndrome

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Reynolds Syndrome should be suspected in CREST patients with persistent cholestatic liver enzymes, since delayed diagnosis allows portal hypertension and variceal bleeding to develop. Early anti‐mitochondrial antibody screening and prompt ursodeoxycholic acid therapy improve outcomes, and these patients need multidisciplinary follow‐up for ...
Ali Gohar   +9 more
wiley   +1 more source

Educational Case: Connective tissue disorders: Sjögren's syndrome. [PDF]

open access: yesAcad Pathol
Patterson AS   +2 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy