Sjögren's syndrome-focusassist: lymphocytic focus assessment in Sjögren's syndrome: a deep learning and spatial analysis approach. [PDF]
Zhang J +14 more
europepmc +1 more source
Trends and Research Hotspots in Biomarkers of Sjögren's Syndrome Over the Past Two Decades: A Data-Driven Atlas Analysis. [PDF]
Zhang X, Li H, Zhou X, Qi S, Li S.
europepmc +1 more source
The rapid integration of immune checkpoint inhibitors (ICIs) into standard oncology protocols has birthed a new frontier in clinical rheumatology: immune‐related adverse events (irAEs). By disrupting the programmed cell death‐1 (PD‐1)/PD‐L1 and cytotoxic T‐lymphocyte‐associated protein 4 (CTLA‐4) axes to restore antitumor T cell activity, these ...
Xizi Hu +3 more
wiley +1 more source
Ophiopogonin D Mediates Therapeutic Effects on Primary Sjögren's Syndrome by Modulating Gut Microbiota and Metabolite Profiles. [PDF]
Pang F, Shan X, Kong Y, Tang X.
europepmc +1 more source
Objective To investigate SARS‐CoV‐2 viral shedding duration in autoimmune patients using B cell depleting (BCD) therapy or tumor necrosis factor inhibitors (TNFi) and immunocompetent comparators. Methods We conducted a matched cohort analysis among participants in POSITIVES, a prospective study enrolling outpatients with acute COVID‐19 within five days
Liya Sisay Getachew +34 more
wiley +1 more source
mTOR signaling pathway in primary Sjögren's syndrome: Pathogenesis and potential therapeutic targets (Review). [PDF]
Huo R +6 more
europepmc +1 more source
METTL3‐mediated m6A modification stabilizes KDR/Kdr mRNA through YTHDC2, amplifying the VEGFA‐KDR feedback loop and disturbing Th17/Treg balance. This pathway promotes persistent inflammation and tissue damage in patients with AIT, and inhibiting the METTL3‐KDR axis effectively disrupts this circuit, alleviating thyroid tissue injury and disease ...
Qingyi Hu +7 more
wiley +1 more source
Shared gene signatures between rheumatoid arthritis and Sjögren's syndrome. [PDF]
Li YF +6 more
europepmc +1 more source
Overlap of Primary Biliary Cholangitis and Systemic Sclerosis: A Case of Reynolds Syndrome
ABSTRACT Reynolds Syndrome should be suspected in CREST patients with persistent cholestatic liver enzymes, since delayed diagnosis allows portal hypertension and variceal bleeding to develop. Early anti‐mitochondrial antibody screening and prompt ursodeoxycholic acid therapy improve outcomes, and these patients need multidisciplinary follow‐up for ...
Ali Gohar +9 more
wiley +1 more source
Educational Case: Connective tissue disorders: Sjögren's syndrome. [PDF]
Patterson AS +2 more
europepmc +1 more source

