Results 171 to 180 of about 37,519 (224)

Pharmacogenomics of Thiopurine Drugs: A Bench‐To‐Bedside Success Story in Thailand

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Thiopurine drugs are the cornerstone treatment for many diseases such as acute lymphoblastic leukemia (ALL), organ rejection, inflammatory bowel disease (IBD), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and other autoimmune diseases.
Mohitosh Biswas, Shobana John, Murshadul Alam Murad, Chonlaphat Sukasem   +3 more
wiley   +1 more source

Complete Heart Block in the Fetus: An Antenatal Complication of Sjögren's Syndrome. [PDF]

Life (Basel)
Videnie M, Poalelungi CV, Chiriac A, Bobircă A, Alexandru MC, Ceaușu I.   +5 more
europepmc   +1 more source

First‐in‐Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASP1617, a Cathepsin‐S Inhibitor, in Healthy Adult Subjects

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT ASP1617 is a novel, highly selective inhibitor of cathepsin‐S, an important protease for antigen peptide loading onto major histocompatibility complex class II molecules. Preclinically, ASP1617 prevented progression of lupus‐like glomerulonephritis in an NZB/W F1 mouse model of systemic lupus erythematosus.
Tomoki Kojima, Wei Chen, Ronald Smulders, Stephen Stanhope, Donna Kowalski, Nakyo Heo, Selina Moy, Amanda Goldston, David Han, Tong Zhu   +9 more
wiley   +1 more source

Eosinophilic Sialodochitis Mimicking Sjögren's Syndrome. [PDF]

Cureus
Sasidharan A, Carter S, Walsh H, Platais C.   +3 more
europepmc   +1 more source

Snapshot Look at Castleman Disease

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Castleman disease (CD) is a rare and heterogeneous group of lymphoproliferative disorders characterised by abnormal proliferation of lymphoid tissue. First described in the 1950s, it has since been classified into two major clinical forms: unicentric CD (UCD), involving a single lymph node region and multicentric CD (MCD), which affects ...
Ciprian Jitaru, Natalia Zlampa, Delia Dima, Anca Bojan, Mihnea Zdrenghea, Laura Urian, David Kegyes, Anamaria Bancos, Maria Santa, Andrei Ivancuta, Bobe Petrushev, Madalina Nistor, Bogdan Tigu, Catalin Constantinescu, Bogdan Fetica, Maria Puiu, Mihai‐Stefan Muresan, Ciprian Tomuleasa   +17 more
wiley   +1 more source

Evaluation of patients diagnosed with primary Sjogren's syndrome with and without pulmonary involvement. [PDF]

Sarcoidosis Vasc Diffuse Lung Dis
Ozsoy Z, Ozdemırel TŞ, Ensarıoğlu K, Erturk H, Ozturk Z, Yıldırım H, Akkurt ES, Beyan E, Kalyoncu U, Ozyurek BA.   +9 more
europepmc   +1 more source

Risk factors for persistent decline in eGFR of Japanese patients with diabetes: Analysis using a large‐scale diabetes registry J‐DREAMS

Journal of Diabetes Investigation, Volume 17, Issue 2, Page 242-255, February 2026.
ABSTRACT Aims/Introduction This study aimed to identify clinical predictors associated with sustained decline in estimated glomerular filtration rate (eGFR) among Japanese individuals diagnosed with diabetes mellitus. Materials and Methods We conducted a retrospective analysis using J‐DREAMS (Japan Diabetes compREhensive database project based on an ...
Kota Yamada, Mitsuru Ohsugi, Yuichiro Ito, Hiroki Uchida, Takumi Lee, Kohjiro Ueki   +5 more
wiley   +1 more source

Interstitial Lung Disease Secondary to Sjogren's Syndrome and Antisynthetase Syndrome: Converging Disease Trajectories. [PDF]

Medicina (Kaunas)
Muscato G, Morina G, Fagone E, Fruciano M, Gili E, Martella S, Palmucci S, Sambataro D, Vancheri C, Sambataro G.   +9 more
europepmc   +1 more source

Cryoglobulinemia: An update on classification, pathophysiology, clinical presentation, and management

Journal of Internal Medicine, Volume 299, Issue 2, Page 196-215, February 2026.
Abstract Cryoglobulinemia (CG) is defined by the presence of serum immunoglobulins that precipitate below 37°C and redissolve upon rewarming. It is classified into three types based on immunoglobulin composition. Type I, a rare form, involves monoclonal IgM or IgG and is linked to lymphoproliferative disorders.
Anna Linda Zignego, Laura Gragnani, Marcella Visentini, Riccardo Bomben, Luca Arcaini, Clodoveo Ferri, Valter Gattei, Cesare Mazzaro   +7 more
wiley   +1 more source

The 'target tissues' as orchestrators of autoimmune responses: the paradigm of Sjögren's syndrome. [PDF]

Clin Exp Immunol
Filika M, Katsiougiannis S.
europepmc   +1 more source