Results 31 to 40 of about 1,159,973 (256)

DIAGNOSIS OF THE SYNDROME OF SCHEGREN. REVIEW

Медична наука України, 2018
Relevance. Sjogren's syndrome is included in the group of diffuse connective tissue diseases and ranks third among them. Sjögren's syndrome remains unidentified in half the cases of the disease with clinical manifestations.
D.V. Topchy
doaj   +1 more source

Primary sjögren’s syndrome and cardiovascular disease

, 2020
Sjögren’s syndrome is a rheumatic autoimmune disease that primarily affects middle-aged women and runs a slowly progressing course with sicca symptoms being the prevalent manifestation.
Melissaropoulos K., Bogdanos D., Dimitroulas T., Sakkas L.I., Kitas G.D., Daoussis D.
core   +1 more source

Autoimmune Comorbidities as Modifiers of Phenotypic Heterogeneity in Facioscapulohumeral Dystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral dystrophy type 1 (FSHD1) shows clinical heterogeneity that is only partly explained by D4Z4 repeat unit (RU) size. Although immune and inflammatory mechanisms may contribute to disease variability, the prevalence and clinical impact of autoimmune diseases in FSHD remain unclear.
Jonathan Pini, Giulia Tammam, Andra Ezaru, Manuela Gambella, Benoît Sanson, Luisa Villa, Michele Cavalli, Mihai‐Bogdan Ioncea, Angela Puma, Sabrina Sacconi   +9 more
wiley   +1 more source

Primary Sjogren’s Syndrome with Bicytopenia: A Case Report

Journal of Nepal Medical Association
Sjogren’s syndrome is a chronic multisystem autoimmune disease presenting a wide variety of clinical manifestations ranging from mild sicca symptoms to severe systemic symptoms involving pulmonary, renal, musculoskeletal, cutaneous, and haematological ...
Deepankar Raj Pathak, Ashish Kumar Chaurasiya, Rasish Subedi, Prabin Khatri, Pooja Shah   +4 more
doaj   +1 more source

An Unusual Initial Presentation of Sjögren’s Syndrome: Severe Hypokalemic Paralysis Secondary to Distal Renal Tubular Acidosis

Eurasian Journal of Medicine, 2019
Sjögren’s syndrome is mainly affects the exocrine glands. Patients usually complain of persistent dryness of the mouth and eyes. However, nonexocrine organs such as the kidneys are often affected in these patients.
Erkan Sengul, Fatih Bunul, Ayten Yazici, Aysun Sengul, Sevim Dindar, Gökçen Selma Kilic Halhalli, Emine Binnetoglu   +6 more
doaj   +1 more source

B-cell activity markers are associated with different disease activity domains in primary Sjögren’s syndrome [PDF]

, 2018
Objectives B-cell activating factor (BAFF), β-2 microglobulin (β2M) and serum free light chains (FLCs) are elevated in primary SS (pSS) and associated with disease activity.
Hallinan, Jennifer, Katherine James, Wan-Fai Ng, Fisher, Benjamin A, Antony Parker, Stephen Harding, UK Primary Sjögren’s Syndrome Registry,, Gillespie, Colin S, Chimwemwe Chipeta, Francesca Barone, Simon J Cockell, Cockell, Simon J, Colin S Gillespie, Barone, Francesca, Bowman, Simon J, Simon J Bowman, Ng, Wan-Fai, null null, James, Katherine, Chipeta, Chimwemwe, Harding, Stephen, Benjamin A Fisher, Parker, Antony, Jennifer Hallinan   +23 more
core   +1 more source

Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights From a Large International Sicca Registry

Arthritis Care &Research, EarlyView.
Objective The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögren's International Collaborative Clinical Alliance (SICCA) cohort. Methods We performed a retrospective analysis examining 16 ocular symptoms (most graded 0–4) and artificial tear (AT) use (graded 0–3) as predictors of DED signs (abnormal ocular ...
Pragnya R. Donthineni, Chloe Shields, Rohit Muralidhar, Shreya Bhatt, Alan Baer, Robert Fox, Sara S. McCoy, Anat Galor   +7 more
wiley   +1 more source

Fibrous histiocytoma as first presentation in systemic lupus erythematosus and sero-positive Sjögren's syndrome

American Journal of Ophthalmology Case Reports, 2018
Purpose: To describe a triad of fibrous histiocytoma, Systemic Lupus Erythematosus and Sero-positive Sjögren's Syndrome. Observations: This case was diagnosed first as bilateral fibrous histiocytoma of cheeks, which on further investigations proved to be
Abdullah Al-Mujaini, Kashinatha Shenoy, Upender Wali   +2 more
doaj   +1 more source

A Scoping Review and Meta‐Analysis of Proportions of Central Nervous System Manifestations Reported in Patients with Sjögren's Disease

Arthritis Care &Research, Accepted Article.
Objective The objective of this scoping review was to synthesize evidence on the proportion of individuals living with Sjögren's disease who experience central nervous system (CNS) manifestations. Methods We searched MEDLINE (via PubMed) and Embase from 1980 through January 29, 2026, and the ECRI Guidelines Trust from 2020 through January 29, 2026 ...
Arun Varadhachary, Ghaith Noaiseh, Julie Frantsve‐Hawley, Frederick B. Vivino, Jennifer A. McCombe, Shamik Bhattacharyya, E. Sherwood Brown, Andrew R. Carey, Robert Fox, Thomas Grader‐Beck, Janet E. Lewis, Stephen Maitz, Steven Mandel, Astrid Rasmussen, George Sarka, R. Hal Scofield, Daniel J. Wallace, Rochelle Zak, Kristie Cox, Katherine M. Hammitt, Steven Carsons, Nancy Carteron   +21 more
wiley   +1 more source

Embedding patient engagement in the R&D process of a life sciences company through co-creation with a patient expert R&D board: a case study

Research Involvement and Engagement
Patient involvement is crucial in healthcare, a factor increasingly recognised by life sciences companies and research institutes. This article presents a case study on Servier, a life sciences company that founded a patient expert board, ahead of ...
Estelle Jobson, Marta Garcia, Danika Sharek, Laura Risueño, Sylvain Arnould, Aude Lemoine-André, Jan Geissler, Ana Amariutei, Sabrina Grigolo, Begonya Nafria Escalera, Thomas Smith, Oriana Sousa, Linda Stone, Janet West   +13 more
doaj   +1 more source