Results 131 to 140 of about 38,700 (229)

Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy

Immunology &Cell Biology, EarlyView.
IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley   +1 more source

Case Report: Autoimmune-associated tubulointerstitial nephritis with predominant Sjögren features in a child presenting with recurrent sterile pyuria. [PDF]

Front Pediatr
Han T, Chang H, Nie N, Liu J, Zhang R, Lin Y, Bai C, Gao S, Zhang Q, Wang D.   +9 more
europepmc   +1 more source

The Role of Innate Lymphoid Cells in Autoimmune, Allergic and Infectious Diseases: A Systematic Review

Immunology, EarlyView.
This systematic review establishes disease‐specific dysregulations of human innate lymphoid cells (ILCs), demonstrating that an ILC1/ILC3 imbalance compromises mucosal barriers in inflammatory bowel disease, while activated ILC2s drive allergic airway inflammation.
Luan F. Lückmann, Henrique R. Dal‐Pizzol, Louise M. Lückmann, Davi E. Salini, Bruna C. Hasckel, Mikaeli Minati, Bruno Kluwe‐Schiavon, Tatiana Barichello   +7 more
wiley   +1 more source

Detecting Sjögren's Disease from Parotid Gland Ultrasound Radiomics. [PDF]

Rheumatology (Oxford)
Akkuzu G, Durugol OF, Tolu S, Dasdelen MF, Karagulle M, Suleyman K, Karaalioğlu B, Deniz R, Özgür DS, Yıldırım F, Bes C.   +10 more
europepmc   +1 more source

Cumulative effects of lifelong systemic excess growth hormone on postcranial skeletal morphology in adult mice

Journal of Anatomy, EarlyView.
Our μCT‐based pilot study reveals size and shape disparity in the adult postcranial skeleton of growth‐hormone model (bGH) mice relative to wild‐type mice. bGH mice have larger and more sexually dimorphic bones, with a systemic radiodensity increase in bony sesamoids and associated, but typically uncalcified, soft tissues.
Joseph R. Groenke, Huanhuan Liu, Grace Lach, Abhishek Wajpe, Darlene Berryman, John J. Kopchick, Shouan Zhu, Patrick M. O'Connor   +7 more
wiley   +1 more source

Diagnostic performance of salivary gland ultrasonography using the OMERACT scoring system in Sjögren disease: A cross-sectional diagnostic accuracy study. [PDF]

Ther Adv Musculoskelet Dis
Hossain MI, Choudhury MR, Majumder MSM, Shazzad MN, Azad MAK, Hassan MM, Bhuiyan R, Hasan MS.   +7 more
europepmc   +1 more source

Placental malperfusion and angiogenesis‐related proteins are associated with small‐for‐gestational‐age in systemic lupus erythematosus

Journal of Internal Medicine, EarlyView.
Abstract Background Although systemic lupus erythematosus (SLE) pregnancy frequently results in small for gestational age (SGA) infants, the understanding of underlying mechanisms is limited. We aimed to identify specific histological patterns of placental injury in SGA in SLE and to explore whether an altered balance of angiogenesis‐related proteins ...
Marit Stockfelt, Henri Puttonen, Ing‐Marie Fyhr, Agnes Torell, Kerstin Andersson, Iva Gunnarsson, Elisabet Svenungsson, Agneta Zickert, Maria Majczuk Sennström, Estelle Trysberg, Anders A. Bengtsson, Andreas Jönsen, Helena Strevens, Christopher Sjöwall, Muna Saleh, Sofia Pihl, Dag Leonard, Lars Rönnblom, Tansim Akhter, Bo Jacobsson, Anna‐Carin Lundell, Anna Rudin   +21 more
wiley   +1 more source

Salivary Viscosity as a Non‐Invasive Candidate Biomarker Associated With Aspiration Risk in Oculopharyngeal Muscular Dystrophy

Journal of Oral Rehabilitation, EarlyView.
Patients with oculopharyngeal muscular dystrophy exhibit disease‐specific salivary hyperviscosity that tracks with dysphagia severity and airway invasion. Non‐invasive chairside screening of salivary viscosity may enable clinicians to stratify aspiration risk during routine care to prevent severe pulmonary complications.
Alex Zvulunov, Rawan Saif, Liraz Olmer, Merav Ben‐David, Limor Benyamini, Amir Dori, Noam Yarom, Lior Greenbaum, Ephraim Tzur, Silvina Friedlander‐Barenboim   +9 more
wiley   +1 more source

Atypical Sjögren-Like Presentation as a Paraneoplastic Manifestation of Metastatic Parotid Adenocarcinoma. [PDF]

Cureus
Berrocal C, Libreros Mejia I, Vallejo-Serna R, Zamora Segura BD, Pineda Bocanegra JL, Barrios Torrejano G, Ariza Martinez M, Arias Molina NA, Barrera Vergara LI.   +8 more
europepmc   +1 more source

Long‐Term Care of OLP Patients: A Retrospective Study From a Single Hospital Outpatient Clinic

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Oral lichen planus (OLP) is a chronic immune‐mediated disorder with malignant potential. However, its real‐world clinical course remains incompletely characterized. This study aimed to describe the natural clinical–histopathological trajectory of OLP in a single tertiary centre and to identify factors associated with dysplasia and ...
F. Scilla, G. Gioco, L. Ferrero, R. Castagnola, A. Zafarone, L. Cimino, M. Tranfa, C. Rupe, C. Lajolo   +8 more
wiley   +1 more source