Results 191 to 200 of about 62,480 (248)

Epidemiology and Genetics of Rheumatic Diseases Suggest a Constant Rate of DNA Damage as Underlying Cause

Immunology, Volume 177, Issue 4, Page 736-748, April 2026.
A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley   +1 more source

Incidence, prevalence and mortality of anorexia nervosa in individuals with childhood-onset type 1 diabetes: a nationwide retrospective cohort study in Sweden. [PDF]

BMJ Open
Sjögren M, Englund E, Erlandsson AÅE, Möllsten A.   +3 more
europepmc   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source

[Single-cell RNA sequencing of B cells reveals molecular typing in Sjögren syndrome]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Lin W, Xie Y, Wang F, Wang S, Liu X, Hu F, Jia Y.   +6 more
europepmc   +1 more source

Sergei Mariev (ed.), Byzantine Perspectives on Neoplatonism. Byzantinisches Archiv, Series Philosophica 1, Boston/Berlin, de Gruyter 2017, 289 p., ISBN 978-1-5015-1167-7. [PDF]

, 2019
Calian, Florin George
core  

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

A study of clinical manifestations and associated factors in photosensitive patients with systemic lupus erythematosus. [PDF]

Eur J Med Res
He JH, Song ZQ, Hui-Li, Kang YJ.
europepmc   +1 more source

Association of Abatacept With Lower Mortality Risk Compared to Rituximab in Rheumatoid Arthritis–Associated Interstitial Lung Disease: An Emulated Target Trial

Arthritis &Rheumatology, Volume 78, Issue 3, Page 592-602, March 2026.
Objective The optimal treatment strategy for rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) remains uncertain, and direct comparative data between biologics are limited. This study aimed to evaluate the effectiveness and safety of abatacept compared with rituximab in patients with RA‐ILD.
Po‐Cheng Shih, Shiow‐Ing Wang, James Cheng Chung Wei   +2 more
wiley   +1 more source

Biomarkers of Lupus Nephritis Histopathology: Where Do We Stand?

Arthritis &Rheumatology, Volume 78, Issue 3, Page 548-557, March 2026.
Objective Lupus nephritis (LN) is characterized by a variable disease course, necessitating continuous monitoring. There is an urgent need to identify noninvasive biomarkers. By reviewing and critically assessing the quality of existing studies on LN biomarkers correlating with histopathology, we here explore the challenges in promoting their use in ...
Valentina Querin, Leonardo Palazzo, Agnes B. Fogo, Mark Haas, David R. W. Jayne, Liz Lightstone, Brad H. Rovin, Surya V. Seshan, Augusto Vaglio, Ioannis Parodis, Ingeborg M. Bajema, for the Lupus Nephritis Classification Steering Committee   +11 more
wiley   +1 more source

Nephrotic syndrome associated with Guillain-Barré syndrome and Sjögren syndrome: A case report and literature review. [PDF]

Medicine (Baltimore)
Guo P, Zhang P, Zhao JW, Wang AY, Wang W.   +4 more
europepmc   +1 more source