Results 241 to 250 of about 107,264 (291)

Identification of SDC1 as a Key Regulator and Therapeutic Target in Rheumatoid Arthritis via JAK2‐STAT3 Pathway

International Journal of Rheumatic Diseases, Volume 29, Issue 2, February 2026.
ABSTRACT Introduction Rheumatoid arthritis (RA) is a chronic autoimmune disorder with unclear molecular mechanisms, complicating early diagnosis and treatment. This study aimed to identify hub genes and pathways driving RA pathogenesis and assess their therapeutic potential.
Gan Cao, Zhihui Wu, Yatao Du, Dongxue Dai, Yang Sun, Xi Jia, Huixin Cai   +6 more
wiley   +1 more source

Histological analysis of age-related degeneration in human female and male knee cartilage and meniscus. [PDF]

Osteoarthr Cartil Open
Sjögren A, Bodahl S, Hughes V, Turkiewicz A, Aspberg A, Hellberg I, Karjalainen VP, Ali N, Önnerfjord P, Englund M.   +9 more
europepmc   +1 more source

Intravitreal anti‐vascular endothelial growth factor injections and risks of stroke in patients with neovascular age‐related macular degeneration—A registry‐based cohort study

Acta Ophthalmologica, Volume 104, Issue 1, Page 98-105, February 2026.
Abstract Background Intravitreal Anti‐Vascular Endothelial Growth Factor (VEGF) rescues retinal vasculatures and prevents disease progression in patients with neovascular Age‐Related Macular Degeneration (nAMD). However, systemic anti‐VEGF may increase the risk of thromboembolic related complications including stroke and TIA. This study aims to explore
A. H. Falemban, K. Söderberg‐Löfdal, F. Jonsson, S. Almlöf‐Sarman, M. von Euler, I. Westborg   +5 more
wiley   +1 more source

Association between Sjögren syndrome and osteoporosis: A bidirectional Mendelian randomization study. [PDF]

Medicine (Baltimore)
Zhao Q, Li J, Zou J, Wei G, Wang Y, Li X, Xiong X.   +6 more
europepmc   +1 more source

Severe Hepatic Adverse Event Induced by Anti‐HER2 Therapy in Breast Cancer: A Case of Successful Immunotherapy With Baricitinib

ACR Open Rheumatology, Volume 8, Issue 2, February 2026.
Yufei Li, Yifan Wang, Miao Shao, Jing He
wiley   +1 more source

Pharmacogenomics of Thiopurine Drugs: A Bench‐To‐Bedside Success Story in Thailand

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Thiopurine drugs are the cornerstone treatment for many diseases such as acute lymphoblastic leukemia (ALL), organ rejection, inflammatory bowel disease (IBD), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and other autoimmune diseases.
Mohitosh Biswas, Shobana John, Murshadul Alam Murad, Chonlaphat Sukasem   +3 more
wiley   +1 more source

[Clinical efficacy and safety of rituximab in treating renal injury in primary Sjögren syndrome]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Zhao Y, Ni M, Li X, Wang B, Cheng G, He J, Jin Y.   +6 more
europepmc   +1 more source

First‐in‐Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASP1617, a Cathepsin‐S Inhibitor, in Healthy Adult Subjects

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT ASP1617 is a novel, highly selective inhibitor of cathepsin‐S, an important protease for antigen peptide loading onto major histocompatibility complex class II molecules. Preclinically, ASP1617 prevented progression of lupus‐like glomerulonephritis in an NZB/W F1 mouse model of systemic lupus erythematosus.
Tomoki Kojima, Wei Chen, Ronald Smulders, Stephen Stanhope, Donna Kowalski, Nakyo Heo, Selina Moy, Amanda Goldston, David Han, Tong Zhu   +9 more
wiley   +1 more source

SARS-CoV-2 Infection in Sjögren Syndrome can be Complicated by Myelitis and Guillain-Barré Syndrome. [PDF]

Intern Med
Finsterer J.
europepmc   +1 more source

Monitoring Asymptomatic Apical Periodontitis in Root‐Filled Teeth—Results From a One‐Year Follow‐Up Prospective Study

International Endodontic Journal, Volume 59, Issue 2, Page 203-214, February 2026.
ABSTRACT Aim To prospectively investigate the incidence of symptoms and changes in the size of the apical bone destruction in symptom‐free root‐filled teeth with persistent apical periodontitis (AP) over 1 year without treatment. Methodology Patients referred to two specialist endodontic clinics in Västra Götaland, Sweden, with asymptomatic periapical ...
M. Sayady‐Ölander, J. Östlin, V. S. H. Yu, C. Ulin, EndoReco, L. Bjørndal, V. S. Dawson, H. Fransson, F. Frisk, M. Markvart, F. Mota de Almeida, M. Pigg, D. Sebring, E. Wigsten, T. Kvist   +14 more
wiley   +1 more source