Results 271 to 280 of about 107,264 (291)

Regulatory Role of FGL-1 in Interorgan Communication by Controlling T Cell Homeostasis During the Onset of Sjögren Disease. [PDF]

Arthritis Rheumatol
Otsuka K, Ushio A, Nagao R, Matsuzawa S, Arakaki R, Fukuta K, Mouri Y, Tsunematsu T, Ishimaru N.   +8 more
europepmc   +1 more source

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Exocrine function in primary Sjögren syndrome: natural course and prognostic factors

Annals of the Rheumatic Diseases, 2008
Few studies have addressed the natural course of, or prognostic factors for the salivary and lacrimal function in primary Sjögren syndrome (SS). Except for the early stages, glandular function has been seemingly stable, and SS A antigen (SSA) seropositivity and hypocomplementemia may predict a decline in the van Bijsterveld score.
K, Haldorsen, K, Moen, H, Jacobsen, R, Jonsson, J G, Brun   +4 more
openaire   +2 more sources

Primary Sjögren's syndrome presenting as autonomic neuropathy Case report

The Netherlands Journal of Medicine, 1998
Abnormalities of the autonomic nervous system have been described in several connective tissue diseases, but the relation with primary Sjögren's syndrome is unclear. This report describes a patient with primary Sjögren's syndrome who presented with severe autonomic failure. The present knowledge on dysfunction of the autonomic nervous system in primary
Barendregt, PJ, Markusse, HM, Man In 't Veld, AJ (Arie)   +2 more
openaire   +3 more sources

Dry eye in Sjögren's syndrome – characteristics and therapy

European Journal of Ophthalmology, 2022
Background Sjögren's syndrome is an autoimmune disease, and its important feature is the lymphocyte infiltration of exocrine glands, including lacrimal glands.
M. Caban, W. Omulecki, B. Latecka-Krajewska   +2 more
semanticscholar   +1 more source

Sjögren’s Disease, Not Syndrome

Arthritis & Rheumatology, 2021
Sjögren's syndrome should henceforth be known as Sjögren's disease. Our call for this is based on the precedence for such name changes in rheumatology as well as important differences between syndrome and disease.
A. Baer, K. Hammitt
semanticscholar   +1 more source

Interleukin 6 receptor inhibition in primary Sjögren syndrome: a multicentre double-blind randomised placebo-controlled trial

Annals of the Rheumatic Diseases, 2020
Objectives No immunomodulatory drug has been approved for primary Sjögren’s syndrome, a systemic autoimmune disease affecting 0.1% of the population.
R. Felten, V. Devauchelle-Pensec, R. Seror, P. Duffau, D. Saadoun, E. Hachulla, Hatron Pierre Yves, C. Salliot, A. Perdriger, J. Morel, A. Mékinian, O. Vittecoq, J. Berthelot, E. Dernis, V. le Guern, P. Dieudé, C. Larroche, C. Richez, T. Martin, C. Zarnitsky, G. Blaison, P. Kieffer, F. Maurier, A. Dellal, S. Rist, E. Andrès, A. Contis, E. Chatelus, C. Sordet, J. Sibilia, Cécile Arnold, M. Tawk, Ouafaa Aberkane, Lise Holterbach, P. Cacoub, A. Saraux, X. Mariette, N. Meyer, J. Gottenberg   +38 more
semanticscholar   +1 more source

Treatment of primary Sjögren’s syndrome with ianalumab (VAY736) targeting B cells by BAFF receptor blockade coupled with enhanced, antibody-dependent cellular cytotoxicity

Annals of the Rheumatic Diseases, 2019
Objectives To evaluate the efficacy and safety of ianalumab (VAY736), a B cell-depleting, B cell activating factor receptor-blocking, monoclonal antibody, in patients with active primary Sjögren’s syndrome (pSS) in a double-blind, placebo-controlled ...
T. Dörner, M. Posch, Yue Li, O. Pétricoul, M. Cabański, J. Milojevic, E. Kamphausen, M. Valentin, Claudia Simonett, L. Mooney, A. Hüser, H. Gram, F. Wagner, S. Oliver   +13 more
semanticscholar   +1 more source

Endothelial specialization of salivary gland vessels for accelerated lymphocyte transfer in Sjögren's syndrome.

The Journal of rheumatology, 1983
We describe vessels within the lymphocytic infiltrate of the salivary glands in Sjögren's syndrome that are identical to those specialized for lymphocyte transport in lymph nodes. These vessels may represent a mechanism for increased lymphocyte traffic into the gland and thereby contribute significantly to the inflammatory process.
Freemont, A.J., Jones, Carolyn
openaire   +4 more sources

Epidemiology of Sjögren syndrome

Nature Reviews Rheumatology, 2023
Maxime Beydon, Sara S. McCoy, Yann Nguyen, T. Sumida, X. Mariette, R. Seror   +5 more
semanticscholar   +1 more source