Results 121 to 130 of about 19,520 (233)

Australian clinical practice guideline: diagnosis and treatment of idiopathic multicentric Castleman disease

Internal Medicine Journal, EarlyView.
Abstract Idiopathic multicentric Castleman disease (iMCD) is a rare condition. The pathogenesis is incompletely understood; however, interleukin‐6 (IL‐6) is a major mediator. The clinical presentation is heterogeneous, from mild constitutional symptoms to severe multi‐organ failure.
Dipti Talaulikar, Jun Yen Ng, Adam Bryant, Annmarie Bosco, Hugh C. Caterson, Pratyush Giri, Pravin Hissaria, Simon J. Harrison, Stephen Lade, Connull Leslie, Jacinta Perram, H. Miles Prince, Dejan Radeski, Maureen Rischmueller, Craig Wallington‐Gates, Nicholas Weber, Alberta Hoi   +16 more
wiley   +1 more source

Cumulative effects of lifelong systemic excess growth hormone on postcranial skeletal morphology in adult mice

Journal of Anatomy, EarlyView.
Our μCT‐based pilot study reveals size and shape disparity in the adult postcranial skeleton of growth‐hormone model (bGH) mice relative to wild‐type mice. bGH mice have larger and more sexually dimorphic bones, with a systemic radiodensity increase in bony sesamoids and associated, but typically uncalcified, soft tissues.
Joseph R. Groenke, Huanhuan Liu, Grace Lach, Abhishek Wajpe, Darlene Berryman, John J. Kopchick, Shouan Zhu, Patrick M. O'Connor   +7 more
wiley   +1 more source

The Expression and Potential Role of MicroRNAs in Oral Lichen Planus

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Oral lichen planus (OLP) is a chronic T‐cell‐mediated immune disease of unknown aetiology. MicroRNA (miRNAs) are short non‐coding RNAs capable of regulating mRNA and may have roles in T‐cell‐related diseases. The aim of this study was to investigate the profile of miRNAs in OLP patients and its interaction with potential target ...
Mousa Ali Heba, Resteu Anastasia, Werner Andreas, Carrozzo Marco   +3 more
wiley   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Optical coherence tomography angiography to assess for retinal vascular changes in Neuro-Sjögren

Therapeutic Advances in Ophthalmology
Background: Sjögren’s syndrome is an autoimmune disease characterized by sicca symptoms and various extraglandular manifestations including vasculitis. Neurological involvement occurs frequently (Neuro-Sjögren) and often mimics immune neuropathies such ...
Melanie Haar, Franz Felix Konen, Marten A. Gehlhaar, Irene Oluwatoba-Popoola, Emilia Donicova, Marija Wachsmann, Ahmed Lubbad, Katerina Hufendiek, Amelie Pielen, Bettina Hohberger, Christian Mardin, Stefan Gingele, Nils K. Prenzler, Diana Ernst, Torsten Witte, Carsten Framme, Thomas Skripuletz, Tabea Seeliger, Anna Bajor   +18 more
doaj   +1 more source

New Insights Into Diffuse Sclerosing Osteomyelitis: Is There a Role of ANA and Vitamin B6?

Oral Diseases, EarlyView.
ABSTRACT Object Diffuse sclerosing osteomyelitis is a poorly understood chronic disease, which appears predominantly in the mandible. Female patients are more often affected than men. DSO is an ultra‐rare disease and incidence is unknown; diagnosis can be very challenging; pathogenesis is poorly understood.
Katharina Theresa Obermeier, Tim Hildebrandt, Ina Dewenter, Wenko Smolka, Eric Hesse, Philipp Poxleitner, Sven Otto   +6 more
wiley   +1 more source

Oral Microbiome in Systemic Autoimmune Diseases: A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Objective The oral cavity represents a key but underexplored interface between host immunity and microbial communities. The aim of this systematic review was to synthesize current literature on oral microbiota alterations in systemic autoimmune diseases.
Sophie Jung, Eirini Militsi, Olivier Huck   +2 more
wiley   +1 more source

The uncertain role of immunosuppressive agents in Sjögren's syndrome

, 1997
Although Sjögren's syndrome is an autoimmune disorder, immunosuppressive agents have yielded disappointing results in clinical trials. In this paper we summarize our experience using immunosuppressive and cytotoxic agents to treat Sjögren's ...
Linardaki, G., Moutsopoulos, H.M.
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Laser Acupuncture on the Management of Xerostomia in Sjögren's Disease: A Randomized Clinical Trial

Oral Diseases, EarlyView.
ABSTRACT Objectives This study evaluated the efficacy of photobiomodulation (PBM) at acupuncture points for managing xerostomia in patients with Sjögren's Disease. Material and Methods In this randomized, double‐blind clinical trial, 50 patients were assigned to PBM group (n = 22) or sham‐PBM group (n = 28).
Matheus Ferreira Linares, Tainá Duarte dos Santos França, Maria Clara Barros Madureira Ferreira, Michele Gomes do Nascimento, Angela Luzia Branco Pinto Duarte, Luiz Alcino Gueiros   +5 more
wiley   +1 more source

Myelin Oligodendrocyte Glycoprotein Antibody-Associated Optic Neuritis with Sjögren\u27s Syndrome

, 2019
The association between optic neuritis and demyelinating and inflammatory conditions is well established; however, optic neuritis as a presenting sign of Sjögren\u27s Syndrome is rare.
Aman Mittal; Iyza Baig; John Chen; Jeanie Choi; Alla Goldberg; Ore-Ofe Adesina
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