Results 181 to 190 of about 1,171,600 (244)

Advancing In Vivo Chimeric Antigen Receptor T‐Cell Engineering to Accelerate Clinical Translation

MedComm, Volume 7, Issue 10, October 2026.
In vivo CAR‐T cell generation directly engineers endogenous T cells using pre‐manufactured gene delivery vectors that target T cells and deliver CAR‐encoding genetic material. The resulting CAR‐T cells expand in vivo and mediate antigen‐specific cytotoxicity.
Zhenxin Bai, Ming Yi, Shengtao Hu, Dixuan Xue, Luxin Wei, Lifeng Zhang, Zhijun Dai   +6 more
wiley   +1 more source

Therapeutic Potential of Adipose-Derived Mesenchymal Stem Cells Transplantation into the Lacrimal Gland in Patients with Sjögren Syndrome. [PDF]

Korean J Ophthalmol
Mohammadpour M, Ramin S, Sarrami-Forooshani R, Ghorbani S, Ahadi M, Ansari I, Matkarimov AK, Sanati H, Abbasi A.   +8 more
europepmc   +1 more source

Therapeutic Properties and Underlying Mechanisms of Traditional Chinese Medicine in Managing Rheumatoid Arthritis: An Integrative Review of Clinical and Molecular Findings

Phytotherapy Research, Volume 40, Issue 10, Page 6005-6042, October 2026.
The translational research framework integrating TCM for RA. The figure outlines a stepwise framework for the modernization and clinical translation of TCM in RA. Part 1 highlights the inheritance and development of TCM theory, including classical medical texts, traditional herbal knowledge, and syndrome differentiation–based treatment principles. Part
Jianting Wen, Jian Liu, Lei Wan, Fanfan Wang, Yang Li   +4 more
wiley   +1 more source

Association between Sjögren syndrome and osteoporosis: A bidirectional Mendelian randomization study. [PDF]

Medicine (Baltimore)
Zhao Q, Li J, Zou J, Wei G, Wang Y, Li X, Xiong X.   +6 more
europepmc   +1 more source

Associations Between Gut Microbiota and Immune Profiles in Community‐Dwelling Older Adults and the Regulatory Role of Polygonatum odoratum

Aging Cell, Volume 25, Issue 10, October 2026.
Gut Microbiota‐Immune Associations in Community‐Dwelling Older Adults: Role of Polygonatum odoratum. ABSTRACT Aging is often associated with intestinal microbiota imbalance and immune system degeneration. The dysregulation and crosstalk of these two factors markedly elevate the elderly's susceptibility to infections and age‐related diseases ...
Tingting Xia, Hongmei Wu, Tianyi Cui, Wenzhi Yang, Min Zhang, Yuhong Huang, Shengyuan Zhou, Yongsheng Wu, Donglan Yan, Fan Jia, Lin Zhang, Zhi Cui, Jiayao An, Xinqin Zhong, Bin Lv, Xin Zhao, Kaijun Niu, Xiumei Gao   +17 more
wiley   +1 more source

Sjögren Syndrome Candidate Autoantigen AQP5 Triggers AQP4 CNS Autoimmunity Through Self-Antigen Mimicry. [PDF]

Neurol Neuroimmunol Neuroinflamm
Moseley CE, Sagan S, Boquett JA, Spencer CM, Hollenbach JA, Sobel RA, Rothbard JB, Steinman L, Sabatino JJ, Zamvil SS.   +9 more
europepmc   +1 more source

Insights into the modulation of age‐related macular degeneration: Molecular and systems‐level perspectives

Acta Ophthalmologica, Volume 104, Issue S293, Page S4-S35, October 2026.
ENGLISH SUMMARY In developed countries, age‐related macular degeneration (AMD) is the leading cause of visual impairment in the aging population. Understanding of its pathogenesis is limited and the number of patients is predicted to continue rising. AMD is classified into two main forms: dry and neovascular AMD (dAMD and nAMD, respectively).
Hanna Heloterä
wiley   +1 more source

Bilateral Peripheral Facial Nerve Neuropathy as the Presenting Feature of Primary Sjögren Syndrome: A Case Report. [PDF]

Clin Case Rep
Hanaoka R.
europepmc   +1 more source

Kcnn4 Knockout Induces Salivary Gland Fibrosis, Immune Cell Infiltration, and B‐Cell Dysfunction in Mice

Chemical Biology &Drug Design, Volume 108, Issue 4, October 2026.
Kcnn4 deficiency leads to a marked enlargement of salivary glands with increased collagen deposition. Increased infiltration of CD4+, CD8+ T cells and CD19+ B cells into the salivary glands of Kcnn4−/− mice. Proteomic profiling of serum inflammatory proteins demonstrates that Kcnn4 ablation broadly reduces the levels of pro‐inflammatory proteins ...
Yuan Zhang, Siming Zheng, Degui Jiang, Cuiyun Cui, Xuan Zhang, Hanlin Tao, Gongbo Fu, Linna Cheng, Shichao Duan   +8 more
wiley   +1 more source

Extranodal Marginal Zone Lymphoma: Integrating Etiology, Microenvironment, and Genetics Into Clinical Decision‐Making

European Journal of Haematology, Volume 117, Issue 4, Page 849-863, October 2026.
ABSTRACT Extranodal marginal zone lymphoma (EMZL) represents a unique paradigm among indolent B‐cell neoplasms, in which lymphomagenesis is frequently driven by chronic antigenic stimulation within tissue‐specific microenvironments. Persistent infectious or autoimmune triggers promote the development of ectopic lymphoid tissue and sustain B‐cell ...
Mamdouh Skafi, Santino Caserta, Enrica Antonia Martino, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Marco Fiorillo, Eugenio Lucia, Graziella D'Arrigo, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Maria Eugenia Alvaro, Giovanni Tripepi, Fortunato Morabito, Massimo Gentile   +15 more
wiley   +1 more source