Results 191 to 200 of about 4,670 (250)
Models, frameworks, and strategies used to implement digital interventions targeted to youth mental health: a scoping review protocol. [PDF]
BMJ OpenMoss SJ, Zuniga Chacon C, Hekmati FB, Siddiqui SA, Stelfox M, Ahmed SB, Birnie K, Halperin D, Halperin SA, Tutelman PR, Stelfox HT, Fiest KM, Parsons Leigh J. +12 moreeuropepmc +1 more sourceExploring the Synergy of Combining BINAP and tCzBN Motifs Within Multi‐Resonant TADF Emitters to Enhance OLED Performance
Advanced Optical Materials, Volume 14, Issue 24, 25 June 2026.This work presents two MR‐TADF emitters, BINAP‐BN1 and BINAP‐BN2, based on a BINAP core and differing numbers of tCzBN units. Both emitters show similar solution photophysics, but distinct behavior in doped films, where BINAP‐BN1 exhibits higher photoluminescence quantum yield and suppressed aggregation‐induced emission broadening compared to BINAP‐BN2.John Marques dos Santos, Debasish Barman, Rangani Wathsala Weerasinghe, Tomas Matulaitis, David B. Cordes, Aidan P. McKay, Youichi Tsuchiya, Chihaya Adachi, Eli Zysman‐Colman +8 morewiley +1 more sourceEvidence based consensus statements for digital tools to address youth mental health literacy. [PDF]
Sci RepMoss SJ, Siddiqui S, Zuniga Chacon C, Sriskandarajah C, Stelfox M, Gaunce B, Harley M, Smith S, Ahmed SB, Birnie K, Halperin D, Halperin S, Hampson C, Hu J, Leppan L, Nickle A, Russell K, Soo A, Solis M, Stelfox HT, Straus S, Tutelman PR, Wiele Q, Fiest KM, Racine N, Parsons Leigh J. +25 moreeuropepmc +1 more sourceImproving the clinical trial landscape for patients with atypical variants of Alzheimer's disease: a call to action
Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.Abstract
Patients with atypical variants of Alzheimer's disease (AD) often present at a younger age with predominantly non‐amnestic impairments and a more aggressive disease course. Historically, individuals with atypical presentations have not been included in large‐scale clinical trials, which typically focus on late‐onset, sporadic amnestic ...Nick Corriveau‐Lecavalier, Neus Falgàs, Deepti Putcha, Jonathan Graff‐Radford, Keir X. X. Yong, Baayla D. C. Boon, Rosaleena Mohanty, Eric Westman, Colin Groot, David T. Jones, Lea T. Grinberg, Gil D. Rabinovici, Jennifer L. Whitwell, Liana G. Apostolova, Melissa E. Murray, Dustin B. Hammers, Suzanne E. Schindler, Inga Atonsdottir, Elizabeth K. Rhodus, Jonathan M. Schott, Ignacio Illán‐Gala, Ogbuagu Chukwuanugo, Jorge J. Llibre Guerra, Ruth Peters, Erin L. Abner, Carla Abdelnour, Albert Lladó, Renaud La Joie, Leonardo Cruz de Souza, Neguine Rezaii, Dror Shir, Yolande A. L. Pijenburg, Maria C. Carrillo, Bradford C Dickerson, Paul Aisen, Rik Ossenkoppele, Rema Raman +36 morewiley +1 more sourceWhite matter hyperintensities are associated with locus coeruleus atrophy and astrocytic β2‐adrenergic receptor expression
Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.Abstract INTRODUCTION
White matter hyperintensities (WMHs) are a robust marker of brain aging and dementia risk, typically attributed to vascular pathology. However, impaired astrocytic support may also contribute. The locus coeruleus (LC), which degenerates early in aging and Alzheimer's disease, provides widespread noradrenergic projections that ...Victor Vidal, Gonzalo Farías, Carolina Delgado, Paul H. Delano, Rodrigo C. Vergara, Patricia Orellana, Tomás Ossandón, Nicolás A. Crossley, Cecilia Gonzalez‐Campo, Sharon L. Naismith, Raul Gonzalez‐Gomez, Carlos Coronel‐Oliveros, Agustín Ibáñez, Gabriel Wainstein, Robert D. Sanders, James M. Shine, Vicente Medel +16 morewiley +1 more sourceElectrical Impedance Myography Detects Disease Progression over 12 to 24 Months in Facioscapulohumeral Muscular Dystrophy
Annals of Neurology, Volume 99, Issue 6, Page 1545-1554, June 2026.Objective
Targeted therapies for facioscapulohumeral muscular dystrophy (FSHD) are progressing through clinical trials. Electrical impedance myography (EIM) provides a noninvasive biomarker of muscle composition that may be valuable especially in early phase trials. This study evaluated EIM data from a multicenter FSHD cohort over 24 months.Karlien Mul, Michael P. McDermott, Russell J. Butterfield, Bakri Elsheikh, Kate Eichinger, Nicholas E. Johnson, Doris G. Leung, Samantha LoRusso, Leann Lewis, William B. Martens, Perry B. Shieh, Leo H. Wang, Michaela Walker, Rabi Tawil, Jeffrey M. Statland, ReSolve Investigators of the FSHD‐CTRN, Jeffrey Statland, Mazen Dimachkie, Constantine Farmakidis, Mamantha Pasnoor, Duaa Jabari, Omar Jawdat, Melissa Currence, Sandhya Sasidharan, Kiley Higgs, Michaela Walker, Rebecca Clay, Rabi Tawil, Johanna Hamel, Kate Eichinger, Leann Lewis, Samantha LoRusso, Bakri Elsheikh, W. David Arnold, Kristina Kelly, Marco Tellez, Leo H. Wang, Matthew K Preston, Catherine Kieu, Aliya Shabbir, Russell Butterfield, Clark Moser, Melissa McIntyre, Amelia Wilson, Sarah Moldt, Katheryn Wagner, Doris Leung, Andrea Jaworek, Nikia Stinson, Mary Yep, Perry Shieh, Christy Skura, Jennifer Huynh, Nicholas Johnson, Amanda Butler, Aileen Jones, Jodie Howell, Karlien Mul, Valeria Sansone, Elena Carraro, Valentina Franchino, Erica DiNatale, Michael Nani, Sabrina Sacconi, Luisa Villa, Giulia Tammam, Jeremy Garcia, Manuela Gambella, Sandray Ayari +68 morewiley +1 more source