Results 91 to 100 of about 18,718 (235)

Sjogren's syndrome. [PDF]

BMJ, 1967
openaire   +3 more sources

A Phase 2 Trial of Frexalimab, a CD40L Antagonist, in Adolescents and Adults With Recent‐Onset Type 1 Diabetes (FABULINUS): Rationale and Study Design

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas, Baerbel Rotthaeuser, Niels Porksen, Pascale Labard, My‐Liên Nguyên‐Pascal, Mathieu Coudert, Baptiste Berthou, Marie Baccara‐Dinet, Gabor Boka, Mark Peakman, Felix Reschke, Michael J. Haller   +11 more
wiley   +1 more source

Diagnostic Approaches to Sjögren’s Syndrome: a Literature Review and Own Clinical Experience

eJournal of Oral Maxillofacial Research, 2012
Objectives: The purpose of present paper is to critically address the recent advances on diagnostic procedures of Sjögren’s syndrome, taking into account the attained local and systemic features of the disease.
Pedro de Sousa Gomes, Gintaras Juodzbalys, Maria Helena Fernandes, Zygimantas Guobis   +3 more
doaj  

Examining the Role of Artificial Intelligence in Assessment: A Comparative Study of ChatGPT and Educator‐Generated Multiple‐Choice Questions in a Dental Exam

European Journal of Dental Education, EarlyView.
ABSTRACT Aim To compare the item difficulty and discriminative index of multiple‐choice questions (MCQs) generated by ChatGPT with those created by dental educators, based on the performance of dental students in a real exam setting. Materials and Methods A total of 40 MCQs—20 generated by ChatGPT 4.0 and 20 by dental educators—were developed based on ...
Nezaket Ezgi Özer, Yusuf Balcı, Gaye Bölükbaşı, Betul İlhan, Pelin Güneri   +4 more
wiley   +1 more source

Profiles of peripheral B cell subsets in a cohort of primary Sjögren's syndrome patients and their potential clinical significance

Journal of Dental Sciences
Background/purpose: Primary Sjögren's syndrome is a prototypical autoimmune disease, with B cell dysfunction as a dominant feature. Further insights into distribution of B cell subsets in primary Sjögren's syndrome are urgently required to identify the ...
Yixiao Xing, Boya Li, Pan Wei, Hong Hua
doaj   +1 more source

Extranodal Marginal Zone Lymphoma: Integrating Etiology, Microenvironment, and Genetics Into Clinical Decision‐Making

European Journal of Haematology, EarlyView.
ABSTRACT Extranodal marginal zone lymphoma (EMZL) represents a unique paradigm among indolent B‐cell neoplasms, in which lymphomagenesis is frequently driven by chronic antigenic stimulation within tissue‐specific microenvironments. Persistent infectious or autoimmune triggers promote the development of ectopic lymphoid tissue and sustain B‐cell ...
Mamdouh Skafi, Santino Caserta, Enrica Antonia Martino, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Marco Fiorillo, Eugenio Lucia, Graziella D'Arrigo, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Maria Eugenia Alvaro, Giovanni Tripepi, Fortunato Morabito, Massimo Gentile   +15 more
wiley   +1 more source

Grading in Gerodontology: A Framework

Gerodontology, EarlyView.
ABSTRACT Introduction Understanding and anticipating oral health deterioration in older adults requires more than describing their current oral and general health. Risk factors arising from oral, systemic and social domains strongly influence disease progression, care complexity and the ability to maintain function over time.
Falk Schwendicke, Gerry McKenna, Frauke Müller, Azize Bell, Najla Chebib, Cristiane Da Mata, Helena Dujic, Jennifer Gallagher, Barbara Janssens, Danielle M. Layton, Manabu Kanazawa, Anastassia Kossioni, Sabrina Maniewicz, Koichiro Matsuo, Pedro Molinero Mourelle, Annika Neri, Takahiro Ono, Sungkrit Pojmonpiti, Foteini Spyraki, Kittipit Srisanoi, Saif S. Syed, Sayaka Tada, Georgios Tsakos, Terry R. Walton, W. Murray Thomson, Jean‐Philippe Haesler, Sophie Dartevelle, Murali Srinivasan   +27 more
wiley   +1 more source

The Development and Validation of the Partial Denture Experience Questionnaire (P‐DEQ): Reliability and Validity

Gerodontology, EarlyView.
ABSTRACT Introduction This paper describes the development and preliminary validation of the Partial Denture Experience Questionnaire (P‐DEQ), a new, condition‐specific instrument designed to measure the multifaceted impacts of living with removable dentures. Methods The P‐DEQ was developed using a multi‐phase, mixed‐methods design. Item generation was
Barry J. Gibson, Nicolas Martin, Bilal El‐Dhuwaib, Gerry McKenna, Sandra Clifford, Alastair Lomax, Sarah R. Baker   +6 more
wiley   +1 more source

Sjögren’s syndrome: history and challenges in diagnosis

Problemy Pielęgniarstwa
The aim of this study is to provide a comprehensive review and analysis of current diagnostic methods for Sjögren’s syndrome and to highlight the historical progress in diagnosing dry eye syndrome.
Kinga Brzdęk, Szymon Wiśniewski, Olga Domańska, Wiktor Baran, Michał Brzdęk   +4 more
doaj   +1 more source

A Systematic Review and Meta‐Analysis of the Global Prevalence of Dry Mouth in Older Adults

Gerodontology, EarlyView.
ABSTRACT Objective The objective of this study is to update prevalence estimates for xerostomia and salivary gland hypofunction (SGH) among older adults through a systematic review and meta‐analysis. Background Dry mouth is common among older adults but is inconsistently assessed and reported.
Porawit Kamnoedboon, Foteini Spyraki, W. Murray Thomson, Murali Srinivasan   +3 more
wiley   +1 more source