A novel potential method for early diagnosis of Sjogren's syndrome: lacrimal gland color doppler ultrasonography. [PDF]
Cai Y +6 more
europepmc +1 more source
CAR‐T Cells in Ulcerative Colitis: The Renaissance of B‐Cell Targeted Therapy in UC
ABSTRACT A recent New England Journal of Medicine report described the first successful use of anti‐CD19 CAR‐T cell therapy in a patient with multirefractory ulcerative colitis (UC). This exceptional case provides striking proof of concept that B cells and plasma cells can act as key pathogenic drivers in UC.
Zlata Chkolnaia +2 more
wiley +1 more source
Causal associations between Sjögren's syndrome and subtypes of endometrial cancer. [PDF]
Zhu Y, Wu Q, Hu L, Wang L.
europepmc +1 more source
Salivary Extracellular Vesicles: Paradigm Shift in Liquid Biopsy Diagnostics
ABSTRACT Extracellular vesicles (EVs), lipid bilayer nanoparticles released by virtually all cells, serve as essential messengers for intercellular communication. Due to their involvement in several pathophysiological processes, EVs have recently gained considerable attention as potentially diagnostic and prognostic biomarkers for various illnesses ...
Kwanele Xulu +3 more
wiley +1 more source
CSF Anti-Sjögren's Syndrome Antigen A Antibodies and Low Glucose Levels in Sjögren's Syndrome-Associated Aseptic Meningitis: A Case Report. [PDF]
Ueno T +4 more
europepmc +1 more source
This study investigated the bidirectional relationship and shared mechanisms between sarcopenia and osteoporosis using data from the UK Biobank. Our findings indicated that the two conditions may act as reciprocal risk factors, with multiple potential biomarkers mediating the muscle‐bone relationship and suggested possible shared signals between the ...
Siqi Xu +10 more
wiley +1 more source
Chronic rhinosinusitis is a risk factor for interstitial lung disease in Sjogren's syndrome. [PDF]
Schonewald B +4 more
europepmc +1 more source
ABSTRACT Cutaneous crystal‐storing histiocytosis (CSH) is an extremely rare histopathologic finding of histiocytes accumulating crystals of immunoglobulin or paraproteins, often associated with lymphoplasmacytic malignancies. It commonly presents in a wide age range of both female and male adults with a history of a lymphoproliferative disorder ...
Ashton Arlen +3 more
wiley +1 more source
Shared gene signatures between rheumatoid arthritis and Sjögren's syndrome. [PDF]
Li YF +6 more
europepmc +1 more source
Unsupervised Flow Cytometry Reveals a Constant Shift Towards Activated CD4+ T Cell Subsets in APECED
APECED is caused by mutations of AIRE that impair negative selection in the human thymus. Using our optimized unsupervised workflow, we reveal that APECED patients show increased activation of T cells and alterations to their Treg pool as well as a novel T cell population not found among healthy controls.
Joonatan Mattila +6 more
wiley +1 more source

