Results 51 to 60 of about 1,167,016 (249)

Lactate Signal: Modulator of Cellular Energy Production and Anabolism

Advanced Science, EarlyView.
Compartmentalized lactate signaling provides a spatial framework for understanding how lactate‐rich states are generated, transported, sensed, and translated into biological outputs. This Review integrates extracellular, cytosolic, mitochondrial‐associated, and nuclear lactate mechanisms to explain how lactate shapes metabolic adaptation, immune ...
Han Wang, Si‐Yuan Yang, Wei Xu
wiley   +1 more source

Marginal Zone B-Cell Lymphoma of the Lacrimal Gland Secondary to Sjogren’s Syndrome

, 2014
Sjogren’s syndrome is a chronic, autoimmune, inflammatory disease which can affect all exocrine glands, particularly the salivary and lacrimal glands, causing dryness of the mouth and eyes.
Hatice Deniz İlhan, Ahmet Burak Bilgin, Bahar Akkaya, Elif Betül Türkoğlu, Mustafa Ünal   +4 more
core   +1 more source

Immune Complexes Shape the Pathogenicity of Autoantibodies in Systemic Autoimmune Diseases: Insights From an FcγRIIIA‐Reporter Assay

Arthritis &Rheumatology, EarlyView.
Objective Immune complexes (ICs), formed by autoantigen and autoantibody, play a pathogenic role in systemic autoimmune diseases through stimulation of Fcγ receptors (FcγR). However, studies investigating bioactivity of circulating ICs across various diseases remain limited.
Koji Suzuki, Masaru Takeshita, Yuki Imai, Hiroyuki Fukui, Kazunori Furuhashi, Kotaro Matsumoto, Jun Kikuchi, Keiko Yoshimoto, Yuko Kaneko   +8 more
wiley   +1 more source

Quantitative Assessment of Salivary Gland Parenchymal Vascularization Using Power Doppler Ultrasound and Superb Microvascular Imaging: A Potential Tool in the Diagnosis of Sjögren"s Syndrome

Balkan Medical Journal, 2020
Background: Primary Sjögren’s syndrome is a chronic inflammatory autoimmune disease. Minor salivary gland biopsy is the gold standard for the diagnosis of primary Sjögren’s syndrome.
Fethi Emre Ustabaşıoğlu, Selçuk Korkmaz, Ufuk İlgen, Serdar Solak, Osman Kula, Sezin Turan, Hakan Emmüngil   +6 more
doaj   +1 more source

Baseline characteristics of patients with ACA positive and negative primary Sjogren’s syndrome.

, 2021
Baseline characteristics of patients with ACA positive and negative primary Sjogren’s syndrome.
Kyung-Ann Lee (8122577), Se-Hee Kim (831251), Youngjae Park (11312712), Hong Ki Min (9417766), Seung-Ki Kwok (32097), Sang-Heon Lee (26634), Hae-Rim Kim (727476)   +6 more
core   +1 more source

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

Arthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento da Conceicao, Neelanjan Vishnu, Shankara N. Varadarajan, Venugopal R. Bovilla, Rajender K. Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

Pulmonary manifestations of Sjögren's syndrome

European Respiratory Review, 2016
In 9–20% of cases, Sjögren's syndrome is associated with various respiratory symptoms. The most typical manifestations are chronic interstitial lung disease (ILD) and tracheobronchial disease.
Thomas Flament, Adrien Bigot, Benjamin Chaigne, Helene Henique, Elisabeth Diot, Sylvain Marchand-Adam   +5 more
doaj   +1 more source

Distinct Molecular Pathways Supporting Sjögren Disease Clusters and Disease Progression

Arthritis &Rheumatology, EarlyView.
Objective Sjögren disease (SjD) is a heterogeneous autoimmune disease. We aimed to investigate blood transcriptomic signatures and disease progression among three recently defined clusters of patients with SjD: (1) B cell active disease with low symptom burden (BALS), (2) high systemic activity (HSA), and (3) low systemic activity with high symptom ...
Sacha E. Silva‐Saffar, Yann Nguyen, Raphaèle Seror, Jacques‐Eric Gottenberg, Anna Niarakis, Xavier Mariette, Gaetane Nocturne   +6 more
wiley   +1 more source

PROFILE OF NEUROLOGICAL MANIFESTATIONS IN PRIMARY SJOGREN’S SYNDROME

, 2002
Objective. To establish the frequency and the type of the neurologic manifestations in pts with primary Sjogren’s syndrome in Bulgarian population. Material and methods.
R M Sloilov, M S Panchovska, J I Slieilanov   +2 more
core   +1 more source

Coexistent Sjogren’s syndrome and Birt-Hogg-Dube´ syndrome: a case report

, 2023
We report a rare case of Sjogren’s syndrome complicated with Birt-Hogg-Dubé syndrome (BHDS) not previously mentioned in the literature. Further, there is insufficient evidence linking the two diseases.
Cheng Lei, Yongkang Lin, Hong Peng, Binyi Yang, Ting Guo, Danhui Yang, Hong Luo   +6 more
core   +1 more source