Results 191 to 200 of about 1,161,655 (264)

Kcnn4 Knockout Induces Salivary Gland Fibrosis, Immune Cell Infiltration, and B‐Cell Dysfunction in Mice

Chemical Biology &Drug Design, Volume 108, Issue 4, October 2026.
Kcnn4 deficiency leads to a marked enlargement of salivary glands with increased collagen deposition. Increased infiltration of CD4+, CD8+ T cells and CD19+ B cells into the salivary glands of Kcnn4−/− mice. Proteomic profiling of serum inflammatory proteins demonstrates that Kcnn4 ablation broadly reduces the levels of pro‐inflammatory proteins ...
Yuan Zhang, Siming Zheng, Degui Jiang, Cuiyun Cui, Xuan Zhang, Hanlin Tao, Gongbo Fu, Linna Cheng, Shichao Duan   +8 more
wiley   +1 more source

Bilateral Peripheral Facial Nerve Neuropathy as the Presenting Feature of Primary Sjögren Syndrome: A Case Report. [PDF]

Clin Case Rep
Hanaoka R.
europepmc   +1 more source

Extranodal Marginal Zone Lymphoma: Integrating Etiology, Microenvironment, and Genetics Into Clinical Decision‐Making

European Journal of Haematology, Volume 117, Issue 4, Page 849-863, October 2026.
ABSTRACT Extranodal marginal zone lymphoma (EMZL) represents a unique paradigm among indolent B‐cell neoplasms, in which lymphomagenesis is frequently driven by chronic antigenic stimulation within tissue‐specific microenvironments. Persistent infectious or autoimmune triggers promote the development of ectopic lymphoid tissue and sustain B‐cell ...
Mamdouh Skafi, Santino Caserta, Enrica Antonia Martino, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Marco Fiorillo, Eugenio Lucia, Graziella D'Arrigo, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Maria Eugenia Alvaro, Giovanni Tripepi, Fortunato Morabito, Massimo Gentile   +15 more
wiley   +1 more source

Hepatic Carcinoma With Epithelial–Myoepithelial Differentiation and Metachronous Intrahepatic Recurrence Following Curative Resection: A Rare Case Report

Hepatology Research, Volume 56, Issue 10, Page 1556-1561, October 2026.
ABSTRACT Background and Aim Epithelial‐myoepithelial carcinoma (EMC), a malignant tumor with biphasic epithelial and myoepithelial differentiation, is typically a salivary gland neoplasm. Contrastingly, myoepithelial carcinoma (MEC) predominantly comprises myoepithelial cells.
Ryo Nagao, Tomoyuki Abe, Masateru Yamamoto, Yuki Imaoka, Naruhiko Honmyo, Seiichi Shimizu, Shintaro Kuroda, Hiroyuki Tahara, Masahiro Ohira, Kentaro Ide, Tsuyoshi Kobayashi, Tetsuya Nakagiri, Koji Arihiro, Hideki Ohdan   +13 more
wiley   +1 more source

Marinesco-Sjögren Syndrome: A Novel <i>SIL1</i> Variant with In Silico Analysis and Review of the Literature. [PDF]

Life (Basel)
Aslan ES, Eslamkhah S, Akcali N, Yavas C, Karcioglu Batur L, Sengenc E, Yüksel A.   +6 more
europepmc   +1 more source

Entering the Age of Specificity in T Cell Immunity

Immunological Reviews, Volume 343, Issue 1, October 2026.
ABSTRACT The discovery of MHC restriction, the resolution of peptide–MHC structure, and the identification of the T cell receptor gene quickly centered epitope‐level specificity as a core concern of T cell biology. Epitope mapping culminated in functional peptide‐based stimulation assays and tetramer staining, which together provide exquisite ...
Paul G. Thomas
wiley   +1 more source

A Novel SIL1 Variant (p.E342K) Associated with Marinesco-Sjögren Syndrome Impairs Protein Stability and Function. [PDF]

Int J Mol Sci
Ruggieri AG, Marinakis NM, Amodei L, Potenza F, Kampouraki A, Tilemis FN, Pietrangelo L, Viele M, Di Marco F, Del Boccio P, Di Cintio F, Selenti N, Valari M, Federici L, Miele AE, Sallese M, Makrythanasis P.   +16 more
europepmc   +1 more source

Advances in the treatment of systemic lupus erythematosus: Biologicals, small‐molecular agents, and cell‐depleting therapies coming to the clinic

Journal of Internal Medicine, Volume 300, Issue 4, Page 461-479, October 2026.
Abstract Systemic lupus erythematosus (SLE; lupus) remains a particular challenge for the practicing clinician on account of its chronic undulating and unpredictable course, its diverse manifestations, and—until recently—limited treatment options all associated with considerable downsides.
Ronald van Vollenhoven
wiley   +1 more source

Nephrotic syndrome associated with Guillain-Barré syndrome and Sjögren syndrome: A case report and literature review. [PDF]

Medicine (Baltimore)
Guo P, Zhang P, Zhao JW, Wang AY, Wang W.   +4 more
europepmc   +1 more source

Thrombomodulin Shapes Thrombo‐Inflammatory Interactions in Lupus Nephritis

Scandinavian Journal of Immunology, Volume 104, Issue 4, October 2026.
Lupus nephritis is characterized by a distinct thrombo‐inflammatory profile dominated by endothelial activation, with thrombomodulin emerging as the most consistent biological marker of renal involvement in systemic lupus erythematosus. ABSTRACT Lupus nephritis (LN) confers a disproportionate thrombotic risk in systemic lupus erythematosus (SLE) that ...
Mads Lamm Larsen, Lea Dich Pedersen, Annette Gudmann Hansen, Trine Korsgaard Hejlesen, Anders Bengtsson, Anne Voss, Ellen M. Hauge, Susan Due Kay, Bent Deleuran, Julie B. Larsen, Steffen Thiel, Anne Troldborg   +11 more
wiley   +1 more source