Results 51 to 60 of about 16,882 (251)
Gene expression signatures from single‐cell transcriptomics predict Sjögren's syndrome
iMetaOmics, EarlyView.A machine learning‐based 12‐gene signature (SjS.Sig) was developed from scRNA‐seq data of PBMCs from Sjögren's syndrome patients. The model was validated using bulk RNA‐seq datasets and further confirmed through flow cytometry and qPCR analysis in an independent clinical cohort, demonstrating robust diagnostic potential.
Shumin Cheng +20 more
wiley +1 more source
SRM Journal of Research in Dental Sciences, 2014 Sjogren′s syndrome (SS) is a chronic autoimmune disease characterized by the lymphocytic infiltration of salivary and lacrimal glands leading to xerostomia and keratoconjunctivitis sicca.
Mallika Kishore +5 more
doaj +1 more source
iMeta, EarlyView.The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
JEADV Clinical Practice, EarlyView.ABSTRACT Multiple myeloma (MM) is a malignant plasma cell disorder that primarily presents with CRAB symptoms (calcium elevation, renal failure, anemia, and bone abnormalities). In rare cases, MM manifests with systemic complications like skin ulcers, which present management challenges. Here, we report a 78‐year‐old Japanese man with MM and refractory
Naoko Hattori +5 more
wiley +1 more source
Effect of sialagogue on bleeding on probing in Sjögren′s syndrome
Indian Journal of Dental Research, 2013 Background: Bleeding on probing (BOP) is a frequent observation in patients with Sjögren′s syndrome and a sialagogue is routinely prescribed for these patients.
Medha Singh, Athena Papas
doaj +1 more source
Cognitive impairment in patients with Neuro‐Sjögren
Annals of Clinical and Translational Neurology, 2020 Objective Extraglandular neurological manifestations of Sjögren’s syndrome are increasingly recognized, defining the disease entity of Neuro‐Sjögren.
Tabea Seeliger +10 more
doaj +1 more source
Nail Disorders in Systemic Conditions
JEADV Clinical Practice, EarlyView.ABSTRACT Nail findings in children can be indicative of an underlying systemic disease. Many of these findings are seen in multiple entities and are not specific to one disease. The importance of specifically examining for these nail changes cannot be overstated.
Jane Sanders Bellet
wiley +1 more source
Salivary gland scintigraphy in sjögren syndrome
Revista Ciencias Biomédicas, 2011 Sjögren syndrome is a systemic autoimmune disease that mainly affects exocrineglands, such as the salivary and lacrimal glands, causing a decline in their secretions.This disease is also known as Sicca Syndrome.
Betancourt-Piñeres Aiken Felipe +6 more
doaj
Sjögren: unique surname, two men, four syndromes and one disease
Arquivos de Neuro-PsiquiatriaHenrik and Torsten Sjögren (/ˈʃoʊɡrən/ or SHOH–grən) were two Swedish physicians living in the same period, but completely unrelated, except for their notable contributions to Medicine. The first one described keratoconjunctivitis sicca, afterward called
José Vitor Alécio Rodrigues +7 more
doaj +1 more source