SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding +10 more
wiley +1 more source
Automatic pose estimation in newborn infants: Lessons from the Baby Grow study. [PDF]
Sotoodeh MS +5 more
europepmc +1 more source
A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies +14 more
wiley +1 more source
Influence mechanism exploration and machine learning prediction of loess compression deformation coefficient under multi-factor coupling effects. [PDF]
Zhou W, Deng C, Wang J.
europepmc +1 more source
Unmanned aerial vehicles for human detection and recognition using neural-network model. [PDF]
Abbas Y +6 more
europepmc +1 more source
Robotont 3-an accessible 3D-printable ROS-supported open-source mobile robot for education and research. [PDF]
Mõtshärg E +8 more
europepmc +1 more source
DAEF-YOLO Model for Individual and Behavior Recognition of Sanhua Geese in Precision Farming Applications. [PDF]
Sun T, Zhang S, Ren R, Li J, Xia Y.
europepmc +1 more source
Accuracy of intraoral scanners for full-arch implant scanning in the Maxilla using horizontal scanbody. [PDF]
Guimarães AS +7 more
europepmc +1 more source
Numerical study on fatigue failure mechanism of reinforced concrete slabs under coupled action of corrosion and cyclic loading. [PDF]
Wang S, Zhao Q, Song P, Yang F.
europepmc +1 more source
PROGRAM DEVELOPMENT FOR COMPUTATIONAL GRIDS USING SKELETONS AND PERFORMANCE PREDICTION
Parallel Processing Letters, 2002We address the challenging problem of algorithm and program design for the Computational Grid by providing the application user with a set of high-level, parameterised components called skeletons. We descrile a Java-based Grid programming system in which algorithmns are composed of skeletons and the computational resources for executing individual ...
MARTIN ALT +2 more
openaire +1 more source

