Results 101 to 110 of about 39,942 (265)

Current Challenges of Transcription Compartmentalization Research

open access: yesAdvanced Science, EarlyView.
Transcription factors, coactivators, and RNA polymerase II assemble into transcription compartments ranging from small, defined complexes to liquid‐like condensates. This review unifies these seemingly competing descriptions along a single continuum and asks what these compartments have been shown to do, and what they have not, revealing that the most ...
Thomas Quail, Sina Wittmann
wiley   +1 more source

Hume and Reason

open access: yesPrincipia: An International Journal of Epistemology, 2000
In this article I challenge the current view that Hume is a naturalist as well as a sceptic. I hold he is a peculiar kind of rationalist. I argue that his position is best viewed as a philosophical approach designed to accommodate the tendencies of ...
Marco Antonio Frangiotti
doaj  

Agent‐Based Simulations of Lung Tumor Evolution Suggest That Ongoing Cell Competition Drives Realistic Clonal Expansions

open access: yesAdvanced Science, EarlyView.
Computational simulations of tumor evolution are increasingly used to infer the rules underlying cancer growth, with the goal of one day recommending tailored treatments. Here we show that the properties of lung cancer sequencing data are best replicated by a model which assumes that cells compete both to proliferate and survive. ABSTRACT Computational
Helena Coggan   +5 more
wiley   +1 more source

Davidson's Criticism of the Proximal Theory of Meaning

open access: yesPrincipia: An International Journal of Epistemology, 2005
According to the proximal theory of meaning, which is to be found in Quine’s early writings, meaning is determined completely by the correla-tion of sentences with sensory stimulations.
Dirk Greimann
doaj  

Latent Diffusion Process With Mechanistic Guidance For Designing Functionally Graded Metamaterials With Perfect Connectivity

open access: yesAdvanced Science, EarlyView.
A latent diffusion‐based framework is proposed for designing functionally graded metamaterials with perfect connectivity. By integrating vector‐quantized latent representations with mechanistic guidance, the framework enables accurate inverse design toward target elastic properties.
Jongbin Yu, Dosung Lee, Namjung Kim
wiley   +1 more source

Updatable Closed‐Form Evaluation of Arbitrarily Complex Multiport Network Connections

open access: yesAdvanced Electronic Materials, EarlyView.
The inverse design of electrically large wave devices often uses reduced‐order multiport models with discrete optimization, requiring many evaluations of complex interconnections between subsystems that differ only in a few blocks. This paper introduces a closed‐form framework enabling efficient Woodbury low‐rank updates of related, previous ...
Hugo Prod'homme, Philipp del Hougne
wiley   +1 more source

LOS ENSAYOS DE MONTAIGNE COMO PROYECTO POLÍTICO EN LA MUERTE DE MONTAIGNE DE JORGE EDWARDS

open access: yesRevista Chilena de Literatura, 2012
Este trabajo estudia cómo La muerte de Montaigne, de Jorge Edwards, puede ser vista como un intento de convertir el escepticismo que caracteriza los Ensayos de Montaigne en un proyecto político de corte democrático.
Bernat Castany Prado
doaj  

Analog Weight Update Rule in Ferroelectric Hafnia, Using picoJoule Programming Pulses

open access: yesAdvanced Electronic Materials, EarlyView.
Resistive, ferroelectric synaptic weights based on BEOL‐compatible hafnia/zirconia nanolaminates are fabricated. Lateral downscaling the devices below 10 µm2 enables 20 ns programming with electrical pulses, dissipating ≤ 3 pJ. Experimental results show that final conductance state is set by pulse amplitude, and is largely independent of the initial ...
Alexandre Baigol   +7 more
wiley   +1 more source

Exploiting Temperature Effects for Robust Control and Reference Circuits Using Thin‐Film Contact‐Controlled Transistors

open access: yesAdvanced Electronic Materials, EarlyView.
Compact circuits based on contact‐controlled transistors are well‐suited to unsupervised thermal management, sensitive temperature measurement, or temperature‐stable current references. Demonstrated on flexible microcrystalline silicon and supported by simulation, the approach does not require supply voltage regulation, remains manufacturable across ...
Eva Bestelink   +6 more
wiley   +1 more source

Redefining Crystalline Silicon: Unlocking New Horizons in Transparent and Flexible Photovoltaics

open access: yesAdvanced Energy Materials, EarlyView.
Crystalline silicon is presented as a platform for transparent and flexible photovoltaics. This review article outlines design principles for optical strategies to fabricate transparent silicon solar cells, mechanical strategies that mitigate silicon brittleness, and emerging concepts such as singlet‐fission spectral conversion and tandem architectures,
Kangmin Lee
wiley   +1 more source

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