Results 101 to 110 of about 154,358 (296)

Interpretation of overtracing freehand sketching for geometric shapes [PDF]

open access: yes, 2006
This paper presents a novel method for interpreting overtracing freehand sketch. The overtracing strokes are interpreted as sketch content and are used to generate 2D geometric primitives.
Wright, David   +7 more
core  

Podróż z Moskwy do Trojeckiego Klasztoru, z niektórymi historycznymi pamiątkami Nikołaja Karamzina w strukturze czasopisma „Wiestnik Jewropy” oraz całokształcie spuścizny pisarza

open access: yesPolilog: Studia Neofilologiczne, 2018
Memoires and historical commentaries on the way to The Trinity Lavra of St. Sergius by Nikolay Karamzin in the structure of the periodical “Vestnik Evropy” and Karamzin’s literary output Memoires and historical commentaries on the way to The Trinity ...
Magdalena Dąbrowska
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

The use of authentic video in Russian as foreign language teaching on A1 level

open access: yesВестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2018
The usage of authentic materials in foreign languages teaching is one of the basic requirements of communicative approach, which means the highest possible likening of educative process to that of a real communication.
Natalija A. Gridneva   +1 more
doaj  

Zoological sketches

open access: yes
[no abstract in text]
Joseph Wolf, Philip Lutley Sclater
openaire   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Реконструкция творческого метода Г.Ф. Борунова на примере картин «Председатель. Колхозная осень», «Красный трактор», «Иван Ползунов»

open access: yesИскусство Евразии
В статье рассматриваются особенности творческого метода заслуженного художника России Геннадия Фёдоровича Борунова (1928–2008) на примере анализа некоторых центральных живописных произведений в творчестве мастера: «Председатель.
Борунова, В.А.
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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