Results 141 to 150 of about 12,185 (265)

Development and application of a mechanistic model for protein A resolution of a bispecific antibody for process characterization and optimization

open access: yesBiotechnology Progress, EarlyView.
Abstract Regeneron's bispecific technology, based on a fully human IgG antibody construct, consists of two distinct heavy chains and a common light chain co‐expressed in a single cell. The co‐expression of the two distinct heavy chains, one of which contains a dipeptide substitution that ablates Protein A binding, leads to the formation of three ...
Samantha Wadsworth   +4 more
wiley   +1 more source

Purine bias in bacterial genes is driven by runaway transcription. [PDF]

open access: yesNat Microbiol
Dierksheide KJ   +3 more
europepmc   +1 more source

Infinite Functional Versatility, Formidable Limits: Evaluating Gallium‐Based Liquid Metals in Rechargeable Batteries

open access: yesCarbon Energy, EarlyView.
Beyond the hype surrounding the self‐healing properties of gallium‐based liquid metals (Ga‐LMs), this perspective critically examines their functional roles in metal‐ion batteries, highlighting both their underlying merits and the often‐overlooked challenges, including non‐representative design and testing configurations, performance overestimations ...
Turly P. P. Sumanasekara   +7 more
wiley   +1 more source

Review of CFD modelling techniques for single‐phase and multiphase flow in static mixers

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
This review synthesizes computational fluid dynamics (CFD) approaches for static mixers, linking hydrodynamics to pressure drop, particle/droplet distributions, mixing metrics, and heat‐transfer performance to guide modelling choices and design decisions. Abstract Static mixers enable compact and low‐energy intensification.
Jussan Jaeger   +7 more
wiley   +1 more source

In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans

open access: yesCytoskeleton, EarlyView.
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley   +1 more source

A Critical Review of Electrolytes for Sodium‐Zinc Hybrid Ion Batteries: From Liquid to Solid

open access: yesEcoEnergy, EarlyView.
This review systematically discusses the evolutionary roadmap of electrolytes from liquid to quasi‐solid and ultimately to all‐solid‐state structures for aqueous sodium‐zinc hybrid ion batteries (ASZIBs), which focuses the critical bottlenecks of uncontrolled dual‐ion transport and interfacial incompatibility, and proposes corresponding countermeasures
Jiao Huang   +3 more
wiley   +1 more source

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