Results 41 to 50 of about 718,196 (292)

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Elastic Critical Buckling Coefficients for Skew Plates of Steel Structures under Biaxial Normal Stress

Buildings
In steel structures, skew thin steel plates serve as panel zones in structures spanning large spaces (e.g., warehouses and gymnasiums). Considerable research has been conducted on the shear buckling of panels due to seismic loads acting on a structure ...
Kazuya Mitsui, Kikuo Ikarashi, Keiichiro Sada   +2 more
doaj   +1 more source

Lateral Load Distribution for Hollow Slab Bridge: Field Test Investigation

International Journal of Concrete Structures and Materials, 2020
Distribution factors (DFs) for one typical cross-section as specified in the AASHTO LRFD specification can be varied when the bridge parameters such as span length, loading lanes and skew are changed.
Yu Zhao, Xiaozhe Cao, Yongjun Zhou, Gangqiang Wang, Ruixin Tian   +4 more
doaj   +1 more source

Buckling analysis of skew plate assemblies: classical plate theory results incorporating Lagrangian multipliers

, 1995
A procedure is presented for the buckling analysis of prismatic skew plate assemblies subject to invariant in-plane stresses. Based on the exact solution of the plate differential equations, the method of Lagrangian multipliers is used to enforce the ...
York, C.B., Williams, F.W.
core   +1 more source

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

Advanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma, Jinguo Xu, Rongrong Gu, Chuanhui Dong, Te Chen, Yi Mu, Jing Zhu, Yating Wang, Wen Wang, Yingying Zhang, Hongyu Ma, Xiaochen Wang, Sheng Ye, Cheng Cheng   +13 more
wiley   +1 more source

Modelling health scores with the skew-normal distribution [PDF]

, 2009
Health care interventions which use quality of life or health scores often provide data which are skewed and bounded. The scores are typically formed by adding up responses to a number of questions. Different questions might have different weights, but
Stanghellini, E., Hutton, Jane
core  

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu, Xuetong Hao, Yang Zou, Xinglin Chen, Junyan Kong, Chunning Gu, Wenjie Ma, Zhongjun Yang, Huifen Liu, Mengmeng Liu, Xin Tong   +10 more
wiley   +1 more source

Numerical Simulation of Two-roller Rotary Rolling Piercing of a New Heat-resistant Alloy SP2215 Seamless Pipe [PDF]

Teshugang
In the process of rotary rolling and piercing for austenitic heat-resistant alloy， the improper selection of process parameters may result in phenomena such as coarse grain and mixed crystal in the pipe billet， or even fracture during processing， thereby
Liang　Kai, Yao　Zhihao, Xie　Xishan, Wang　Hongying, Cheng　Jian, Dai　Weixing, Dong　Jianxin
doaj   +3 more sources

Experimental and finite element studies on buckling of skew plates under uniaxial compression

Science and Engineering of Composite Materials, 2015
Experimental studies were made on isotropic skew plates made of aluminum 7075-T6 and laminated composite skew plates under uniaxial compression with unloaded edges completely free and one loaded edge restrained completely and the other loaded edge ...
Venkateshappa Srinivasa Chikkol, Jayadevappa Suresh Yalaburgi, Puttiah Prema Kumar Wooday   +2 more
doaj   +1 more source

VIBRATION ANALYSIS OF ROTATING PRE-TWISTED CANTILEVER PLATE BY USING THE FINITE ELEMENT METHOD

Journal of Engineering, 2009
In this paper the finite element method has been used to determine the fundamental natural frequencies of a pre-twisted plate mounted on the periphery of a rotating disc.
Oday I. Abdullah
doaj   +1 more source