Results 41 to 50 of about 2,880,968 (298)

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

A novel deep learning framework with temporal attention convolutional networks for intrusion detection in IoT and IIoT networks

Scientific Reports
The rapid expansion of Internet of Things (IoT) and Industrial Internet of Things (IIoT) networks has significantly increased the vulnerabilities of critical infrastructures to cyberattacks, posing substantial risks to both security and operational ...
Kingkar Prosad Ghosh, Mehedi Hasan, Md. Towhidul Islam Robin, Md. Alamgir Hossain, Md. Samiul Islam   +4 more
doaj   +1 more source

Motivational simulated teaching of clinical skills using formative assessment methods for medical undergraduate students: between-group evaluation of a simulated course in a Chinese medical college

BMJ Open, 2023
Objectives Teaching clinical skills is an important component of educational programmes for medical undergraduates. However, the extension of the interval between the completion of the course and qualification examination affects the performance of ...
Zhen Wang, Wen Yang, Jie Gong, Manzhen Ruan, Miao Peng, Wenfang Xia, Xianzhe Liu, Guangyao Yang   +7 more
doaj   +1 more source

Robust skill of decadal climate predictions

npj Climate and Atmospheric Science, 2019
There is a growing need for skilful predictions of climate up to a decade ahead. Decadal climate predictions show high skill for surface temperature, but confidence in forecasts of precipitation and atmospheric circulation is much lower.
D. Smith, R. Eade, Adam A. Scaife, L. Caron, G. Danabasoglu, T. Delsole, T. Delworth, F. Doblas-Reyes, N. Dunstone, L. Hermanson, V. Kharin, M. Kimoto, W. Merryfield, T. Mochizuki, W. Müller, H. Pohlmann, S. Yeager, X. Yang   +17 more
semanticscholar   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

21st Century Skill “Problem Solving”: Defining the Concept

Asian Journal of Interdisciplinary Research, 2019
Only knowledge is not sufficient to make students succeed in the world. Students need to attain 21st century skills like problem-solving, creativity, innovation, metacognition, communication etc. to endure in the modern world.
Mehadi Rahman Md
semanticscholar   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

An Analysis of Factors Influencing Learners’ English Speaking Skill

, 2017
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Lai-Mei Leong, S. M. Ahmadi
semanticscholar   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source