Results 221 to 230 of about 2,960,039 (306)

Domain-specific motor skill outcomes following a structured play-based motor intervention in preschool children: a cluster-randomized controlled trial. [PDF]

Front Sports Act Living
Agnese M, Massaro S, Cottone R, Scardina A, Lo Dico F, Honório S, Bellafiore M, Tabacchi G.   +7 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Let us tell you how to train us! experiences of children and youth with the Wheelchair Skills Training Program and their preferences for training delivery: a descriptive qualitative study. [PDF]

Front Rehabil Sci
Ouellet B, So S, Dib T, Rushton PW, Hebinck M, Moore SA, Arbour-Nicitopoulos KP, Kirby RL, Routhier F, Best KL.   +9 more
europepmc   +1 more source

Senning procedure in a 4-month-old child with atrioventricular discordance and ventriculoarterial concordanceCentral Message

JTCVS Techniques
Ross M. Ungerleider, MD, MBA, Rob J. Hartman, MD, Sara Pittenger, MD, Robert Hanfland, MD, Neptali Bocanegra, PAC, Scott Buck, MD, Elisabeth Leong, MD, John Cotton, MD, Elman Franz, MD, Ryan Shea, MD, Annie Anderson, PNP, Pamela S. Ro, MD, Timothy M. Hoffman, MD   +12 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Development and psychometric validation of the soft skills scale for primary school students. [PDF]

Front Psychol
Esen Aygün H, Aşıkcan M, Zeren ŞG.
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Exploring the structural relationships between soft skills, emotional intelligence, cognitive flexibility, and self-directed learning in the digital age: A cross-sectional PLS-SEM study of female students of king Faisal University, Saudi Arabia. [PDF]

PLoS One
AlMuhaysh HF.
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source